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Table 3 The correlation between circRNAs and clinicopathologic characteristics in SLE

From: The identification of circular RNAs from peripheral blood mononuclear cells in systemic lupus erythematosus

SLE criterion has-circRNA (fold change > 2.5 means high)
100263 P 103906 P 102489 P 101413 P 101260 P
H L H L   H L H L H L
Malar rash (+) 8 1 0.73 8 1 0.73 6 3 0.49 5 4 0.389 3 6 0.2
Malar rash (−) 1 0   1 0   1 0   1 0   1 0  
Photosenstivity (+) 2 1 0.11 3 0 0.49 3 0 0.292 1 2 0.26 1 2 0.78
Photosenstivity (−) 7 0   6 1   4 3   5 2   3 4  
Discoid rash (+) 2 0 0.6 2 0 0.6 2 0 0.301 2 0 0.197 1 1 0.75
Discoid rash (−) 7 1   7 1   5 3   4 4   3 5  
Oral uclers (+) 1 0 0.73 1 0 0.73 0 1 0.107 1 0 0.389 0 1 0.39
Oral uclers (−) 8 1   8 1   7 2   5 4   4 5  
Arthritis Anti-MPO (+) 2 0 0.6 2 0 0.6 1 1 0.533 1 1 0.747 1 1 0.75
Anti-MPO (−) 7 1   7 1   6 2   5 3   3 5  
Serositis N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A
Renal disorder 2 1 0.11 3 0 0.49 1 1 0.183 2 1 0.667 1 2 0.78
≥ 500 versus < 500 7 0   6 1   6 2   4 3   3 4  
Neurologic disoder N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A N.A
Hematologica disoder                
Leukopenia (+) 3 0 0.49 2 1 0.11 3 0 0.175 1 2 0.26 1 2 0.78
Leukopenia (−) 6 1   7 0   4 3   5 2   3 4  
Lymphopenia (+) 3 0 0.49 3 0 0.49 3 0 0.175 2 1 0.778 2 1 0.26
Lymphopenia (−) 6 1   6 1   4 3   4 3   2 5  
Thrombocytopenia (+) 2 0 0.6 2 0 0.6 0 2 0.016* 1 1 0.747 0 2 0.2
Thrombocytopenia (−) 7 1   7 1   7 1   5 3   4 4  
ANA                
Anti-dsDNA (+) 9 0 0.02* 8 1 0.73 6 0 0.49 5 4 0.389 3 6 0.2
Anti-dsDNA (−) 0 1   1 0   1 3   1 0   1 0  
Anti-Smd1 (+) 2 0 0.6 2 0 0.6 1 1 0.533 1 1 0.747 1 1 0.75
Anti-Smd1 (−) 7 1   7 1   6 2   5 3   3 5  
Immunologic disoders                
IgG (+) 6 0 0.2 5 1 0.39 3 3 0.2 2 4 0.035* 1 5 0.07
IgG (−) 3 1   4 0   4 0   4 0   3 1  
IgM (+) 1 0 0.73 1 0 0.73 1 0 0.49 5 0 0.389 1 0 0.2
IgM (−) 8 1   8 1   6 3   1 4   3 6  
Anti-C3 (+) 6 1 0.49 6 1 0.49 5 2 0.88 4 3 0.778 2 5 0.26
Anti-C3 (−) 3 0   3 0   2 1   2 1   2 1  
Anti-C4 (+) 5 1 0.39 5 1 0.39 4 2 0.778 4 2 0.598 2 4 0.6
Anti-C4 (−) 4 0   4 0   3 1   2 2   2 2  
SLEDAI    0.89    0.78    0.85    0.82    0.8
  1. SLEDAI P means Pearson coefficient, indicated high expression of circRNAs positive related to SLEDAI