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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Analysis of risk allele frequencies of single nucleotide polymorphisms related to open-angle glaucoma in different ethnic groups

Fig. 5

Correlation plots of the prevalence of open-angle glaucoma with intraocular pressure and genetic risk score using related single nucleotide polymorphisms. a The genetic risk score of OAG with high IOP according to populations of different ancestry was highest in Europeans, followed by South Asians, Africans, and East Asians. b The prevalence of OAG with elevated IOP was positively correlated with the population average genetic risk score (R = 0.699). The prevalence of open-angle glaucoma with normal intraocular pressure (normal-tension glaucoma) in AMR was excluded from the analysis since there were not enough research results. AMR: American, EUR: Europeans, SAS: South Asians, AFR: Africans, EAS: East Asians. ACB: African Caribbean in Barbados, ASW: African Ancestry in Southwest US, BEB: Bengali in Bangladesh, CDX: Chinese Dai in Xishuangbanna, CEU: Utah residents with Northern and Western European ancestry, CHB: Han Chinese in Beijing, China, CHS: Southern Han Chinese, China, CLM: Colombian in Medellin, Colombia, ESN: Esan in Nigeria, FIN: Finnish in Finland, GBR: British in England and Scotland, GIH: Gujarati Indian in Houston, TX, GWD: Gambian in Western Division, The Gambia, IBS: Iberian populations in Spain, ITU: Indian Telugu in the UK, JPT: Japanese in Tokyo, Japan, KOR: Korean in Republic Korea, KHV: Kinh in Ho Chi Minh City, Vietnam, LWK: Luhya in Webuye, Kenya, MSL: Mende in Sierra Leone, MXL: Mexican Ancestry in Los Angeles, California, PEL: Peruvian in Lima, Peru, PJL: Punjabi in Lahore, Pakistan, PUR: Puerto Rican in Puerto Rico, STU: Sri Lankan Tamil in the UK, TSI: Toscani in Italy, YRI: Yoruba in Ibadan, Nigeria

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