Fig. 1

DEGs screening. a Volcano map of DEGs. The blue and red dots indicate DEGs that are significantly downregulated and upregulated, respectively. The black horizontal line indicates FDR < 0.05, and the two black vertical lines indicate |log2FC|> 1. b Two-way hierarchical clustering heat map based on DEG expression. In the sample bar, orange and purple represent metastatic and nonmetastatic SKCM tumor samples, respectively. c KM curves of sample prognosis information about cluster 1 and cluster 2, which is obtained by clustering based on DEG expression in the TCGA training dataset. The green and red curves represent cluster 1 and cluster 2 tumor sample groups, respectively. DEGs, differentially expressed genes; SKCM, skin cutaneous melanoma; KM, Kaplan–Meier; TCGA, The Cancer Genome Atlas