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Table 2 Table showing deleted genes in the 16p.11 region in three analysed probands, according to the microarray results

From: Three case reports of patients indicating the diversity of molecular and clinical features of 16p11.2 microdeletion anomaly

  Size of deleted region (kbp) Result of microarray
ISCN 2016
Deleted genes Common deleted genes
Proband #1 1699.55 arr[GrCh37] 16p11.2(28490479_30190029) × 1 CLN3, APOBR, IL27, NUPR1, SGF29, SULT1A2, SULT1A1, NPIPB8, EIF3C, EIF3CL, MIR6862-1, MIR6862-2, NPIPB9, ATXN2L , TUFM, MIR4721, SH2B1, ATP2A1, ATP2A1-AS1 , RABEP2, CD19, NFATC2IP, MIR4517, SPNS1, LAT, RRN3P2, SNX29P2, NPIPB11, SMG1P6, BOLA2-SMG1P6, LOC606724, BOLA2, BOLA2B, SLX1B, SLX1A, SLX1A-SULT1A3, SLX1B-SULT1A4, SULT1A4, SULT1A3, LOC388242, LOC613038, SMG1P2, MIR3680-1, MIR3680-2, SPN, QPRT, C16orf54, ZG16, KIF22, MAZ, PRRT2, PAGR1, MVP, CDIPT, CDIPT-AS1, SEZ6L2, ASPHD1, KCTD13, TMEM219, TAOK2, HIRIP3, INO80E, DOC2A, C16orf92, FAM57B, ALDOA, PPP4C, TBX6, YPEL3, LOC101928595, GDPD3, MAPK3 SMG1P2, MIR3680-1, MIR3680-2, SPN, QPRT, C16orf54, ZG16, KIF22, MAZ, PRRT2, PAGR1, MVP , CDIPT, CDIPT-AS1, SEZ6L2, ASPHD1, KCTD13 , TMEM219, TAOK2 , HIRIP3, INO80E, DOC2A , C16orf92, FAM57B, ALDOA , PPP4C, TBX6 , YPEL3, LOC101928595, GDPD3, MAPK3
Proband #2 610 arr[GrCh37] 16p11.2(29580020_30190029) × 1 SMG1P2, MIR3680-1, MIR3680-2, SPN, QPRT, C16orf54, ZG16, KIF22, MAZ, PRRT2, PAGR1, MVP, CDIPT, CDIPT-AS1, SEZ6L2, ASPHD1, KCTD13, TMEM219, TAOK2, HIRIP3, INO80E, DOC2A, C16orf92, FAM57B, ALDOA, PPP4C, TBX6, YPEL3, LOC101928595, GDPD3, MAPK3
Proband #3 761 arr[GrCh37] 16p11.2(29428531_30190029) × 1 SMG1P6, BOLA2-SMG1P6, LOC606724, BOLA2, BOLA2B, SLX1B, SLX1A, SLX1A-SULT1A3, SLX1B-SULT1A4, SULT1A4, SULT1A3, LOC388242, LOC613038, SMG1P2, MIR3680-1, MIR3680-2, SPN, QPRT, C16orf54, ZG16, KIF22, MAZ, PRRT2, PAGR1, MVP, CDIPT, CDIPT-AS1, SEZ6L2, ASPHD1, KCTD13, TMEM219, TAOK2, HIRIP3, INO80E, DOC2A, C16orf92, FAM57B, ALDOA, PPP4C, TBX6, YPEL3, LOC101928595, GDPD3, MAPK3