New susceptibility alleles associated with severe coronary artery stenosis in the Lebanese population

BMC Medical Genomics

Table 4 Summary table for the SNPs significant for each of the Generalized Linear Models (GLMs)

Lead SNP	Position	Chromosome	A1	A2	Candidate genes	Variant location	p value for association in every model
Lead SNP	Position	Chromosome	A1	A2	Candidate genes	Variant location	Model #1	Model #2	Model #3
rs17005877	79763772	12	G	A	N/A	Intergenic	1.89E−07	N/S	N/S
rs9295937	30961632	6	G	A	NAPGP2	Pseudogene	1.58 E−08	1.18 E−08	N/S
rs9368648	30956152	6	T	C	N/A	Intergenic	2.77 E−09	1.48 E−09	N/S
rs9391637	30945130	6	G	A	MUCL3	Intronic	1.60 E−08	1.19 E−08	N/S
rs12593069	101355666	15	C	T	PCSK6	Intronic	N/S	N/S	7.43 E−10
rs2343305	80468431	10	A	G	TSPAN14	Intronic	N/S	N/S	3.66 E−07
rs6778944	171548961	3	G	T	N/A	Intergenic	N/S	N/S	7.43 E−10
rs7835529	13664494	8	T	C/G	N/A	Intergenic	N/S	N/S	7.45 E−10

The significance level was set at \(5 \times 10^{ - 7}\) for each of the three models and the nucleotide locations and annotation were based on the human genome reference GRCh38/hg18.

ISSN: 1755-8794