Fig. 4

Meta-analysis of other gene variants associated with acne presentation involving immune and inflammatory responses, and sebaceous gland function and activity. a SELL rs7531806. b TGFB rs1159268. c TIMP2 rs8179090. d DDB2 rs747560. e FST rs38055. f IGF1 CA repeat VNTR. g PPARG rs1801282. Only gene variants that were investigated in at least two other previous studies were included in the meta-analysis. Analysis was performed under allele model (minor allele vs. major allele), i.e. A versus G for a, T vs. A for b, C versus G for c, G versus A for d, A versus G for e, 192/192 versus non192/non192 for f, and G versus C for g. OR and CI values for a, d and e for Petridis et al. [11] were derived from the authors’ meta-analysis. OR and CI values for a, d for Navarini et al. [10] were derived from personal communication with the authors, while for e was derived from [11]