Table 4 Associations between PRSs and PA risk
From: Susceptibility loci for pancreatic cancer in the Brazilian population
Type of score | Quintiles | ORa | 95%CIa | p value |
|---|---|---|---|---|
Unweighted, subjects with 100% call rate | 1 | 1.00 | – | Ref |
|  | 2 | 0.44 | 0.09–2.25 | 0.327 |
|  | 3 | 2.61 | 0.97–7.01 | 0.057 |
|  | 4 | 3.29 | 1.15–9.37 | 0.026 |
|  | 5 | 6.83 | 2.76–16.89 | 3.26 × 10–5 |
|  | Continuousb | 1.73 | 1.40–2.15 | 4.30 × 10–7 |
Unweighted scaled, all subjects | 1 | 1.00 | – | Ref |
|  | 2 | 0.65 | 0.16–2.60 | 0.539 |
|  | 3 | 2.22 | 0.86–5.73 | 0.097 |
|  | 4 | 4.03 | 1.57–10.37 | 0.004 |
|  | 5 | 6.70 | 2.86–15.69 | 1.21 × 10–5 |
|  | Continuousb | 1.72 | 1.41–2.10 | 1.02 × 10–7 |
Weighted, subjects with 100% call rate | 1 | 1.00 | – | Ref |
|  | 2 | 2.15 | 0.39–11.75 | 0.376 |
|  | 3 | 3.51 | 0.71–17.29 | 0.122 |
|  | 4 | 4.90 | 1.02–23.56 | 0.047 |
|  | 5 | 16.77 | 3.80–74.07 | 1.99 × 10–4 |
|  | Continuousb | 2.05 | 1.58–2.65 | 4.98 × 10–8 |
Weighted scaled, all subjects | 1 | 1.00 | – | Ref |
|  | 2 | 1.37 | 0.41–4.62 | 0.613 |
|  | 3 | 2.07 | 0.67–6.44 | 0.209 |
|  | 4 | 3.22 | 1.08–9.60 | 0.036 |
|  | 5 | 8.13 | 2.95–22.43 | 5.12 × 10–5 |
|  | Continuousb | 1.76 | 1.42–2.17 | 2.28 × 10–7 |