Fig. 2

Construction of a Risk Assessment Model based on CCRL2, HSPA1A and SCG2. Univariate Cox (a) and multivariate Cox (b) regression analyses for CCRL2, HSPA1A and SCG2. c–e Overall survival analysis for CCRL2, HSPA1A and SCG2 by univariate Cox regression analysis. f The normalized expression of CCRL2, HSPA1A and SCG2 in CRC. Risk scores (g) and survival outcomes (h) of each case of CRC based on CCRL2 and HSPA1A. Risk scores (i) and survival outcomes (j) of each case of CRC based on CCRL2 and HSPA1A. Overall survival analysis of the risk model constructed based on 2 IR-DEGs (CCRL2 and HSPA1A) (k) and 1 DEG (SCG2) (l). m The expression of CCRL2, HSPA1A and SCG2 in different groups of CRC. The ROC curve of the risk model based on 2 IR-DEGs (CCRL2 and HSPA1A) (n) and 1 DEG (SCG2) (o). The AUC values of the 3-year, 5-year and 10-year survival based on 2 IR-DEGs (CCRL2 and HSP1A1) (p) and 1 DEG (SCG2) (q)