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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 disease

Fig. 1

Gene expression differences between dermal fibroblast cell lines derived from the oldest (≥ 80 years) and youngest (≤ 10 years) age groups. a Volcano plot showing gene expression differences between oldest and youngest age groups. b KEGG pathways enriched in differentially expressed genes between the oldest and youngest age groups. c Heatmap of differentially expressed pattern recognition receptor genes between the oldest and youngest age groups. d Violin plots of the pattern recognition receptor genes that had an Adjusted P Value < 0.05 and a log2FC > 1.0 between the oldest and youngest age groups

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