Skip to main content
Fig. 6 | BMC Medical Genomics

Fig. 6

From: In silico analysis suggests disruption of interactions between HAMP from hepatocytes and SLC40A1 from macrophages in hepatocellular carcinoma

Fig. 6

Macrophages in HCC and para-carcinoma tissue samples. a Heatmap of expression of known macrophage markers (ITGAM, CD68, CD163, CD14, and FCGR3A) and SLC40A1 in the UMAP plot. b UMAP plot of all cells from HCC and para-carcinoma tissues. Clusters of macrophages are indicated. c Macrophages in the UMAP plot from different groups were counted. The N_exp group includes cells from para-carcinoma tissue expressing SLC40A1, and the N_noexp group includes cells from para-carcinoma tissue with no SLC40A1 expression. The T_exp group includes cells from HCC tissues expressing SLC40A1, and the T_noexp group includes cells from HCC tissues with no SLC40A1 expression. d KEGG pathway enrichment of marker genes of cluster 10 in the UMAP plot. e Heatmap showing expression of CD5L, CETP, MARCO, CXCL12, PLAC8, VACM1, CFP, LYVE1, and SDC3 in the UMAP plot

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us