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Table 1 Candidate genes by clustering analysis by R software

From: The identification of novel gene mutations for degenerative lumbar spinal stenosis using whole-exome sequencing in a Chinese cohort

GENE Feature_1 Feature_2 N_of_Feature1 N_of_Feature2 FDR
GPRIN2 Patient Normal 45 of 50 0 of 25 2.70983E−15
MYOT Patient Normal 45 of 50 0 of 25 2.70983E−15
PDE4DIP Patient Normal 45 of 50 0 of 25 2.70983E−15
EPPK1 Patient Normal 44 of 50 0 of 25 1.40008E−14
SYT15 Patient Normal 39 of 50 0 of 25 1.14246E−11
CGREF1 Patient Normal 31 of 50 0 of 25 3.2011E−08
IRF5 Patient Normal 25 of 50 0 of 25 3.3725E−06
SIRPB1 Patient Normal 24 of 50 0 of 25 9.2172E−06
HLA-DQA1 Patient Normal 23 of 50 0 of 25 1.06146E−05
MUC6 Patient Normal 19 of 50 0 of 25 0.000141694
PROSER3 Patient Normal 18 of 50 0 of 25 0.000315482
IGFN1 Patient Normal 17 of 50 0 of 25 0.000375298
PABPC1 Patient Normal 16 of 50 0 of 25 0.000728519
KRT79 Patient Normal 9 of 50 0 of 25 0.02508378
FLNA Patient Normal 9 of 50 0 of 25 0.02508378
PHRF1 Patient Normal 9 of 50 0 of 25 0.02508378
ALS2CL Patient Normal 10 of 50 0 of 25 0.025483837
KNSTRN Patient Normal 10 of 50 0 of 25 0.025483837
COL6A5 Patient Normal 8 of 50 0 of 25 0.046170366
TSHZ2 Patient Normal 8 of 50 0 of 25 0.046170366
AADAC Patient Normal 8 of 50 0 of 25 0.046170366
ADAT1 Patient Normal 8 of 50 0 of 25 0.046170366
CMA1 Patient Normal 8 of 50 0 of 25 0.046170366
DEAF1 Patient Normal 8 of 50 0 of 25 0.046170366
DLAT Patient Normal 8 of 50 0 of 25 0.046170366
DST Patient Normal 8 of 50 0 of 25 0.046170366
FLG Patient Normal 8 of 50 0 of 25 0.046170366
KIAA0556 Patient Normal 8 of 50 0 of 25 0.046170366
LPA Patient Normal 8 of 50 0 of 25 0.046170366
P2RX5 Patient Normal 8 of 50 0 of 25 0.046170366
PANK2 Patient Normal 8 of 50 0 of 25 0.046170366
RASSF4 Patient Normal 8 of 50 0 of 25 0.046170366
WARS Patient Normal 8 of 50 0 of 25 0.046170366
ZNF572 Patient Normal 8 of 50 0 of 25 0.046170366
  1. Frequency of allele mutations were zero in controls and FDR < 0.05