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Table 1 Candidate genes by clustering analysis by R software

From: The identification of novel gene mutations for degenerative lumbar spinal stenosis using whole-exome sequencing in a Chinese cohort

GENE

Feature_1

Feature_2

N_of_Feature1

N_of_Feature2

FDR

GPRIN2

Patient

Normal

45 of 50

0 of 25

2.70983E−15

MYOT

Patient

Normal

45 of 50

0 of 25

2.70983E−15

PDE4DIP

Patient

Normal

45 of 50

0 of 25

2.70983E−15

EPPK1

Patient

Normal

44 of 50

0 of 25

1.40008E−14

SYT15

Patient

Normal

39 of 50

0 of 25

1.14246E−11

CGREF1

Patient

Normal

31 of 50

0 of 25

3.2011E−08

IRF5

Patient

Normal

25 of 50

0 of 25

3.3725E−06

SIRPB1

Patient

Normal

24 of 50

0 of 25

9.2172E−06

HLA-DQA1

Patient

Normal

23 of 50

0 of 25

1.06146E−05

MUC6

Patient

Normal

19 of 50

0 of 25

0.000141694

PROSER3

Patient

Normal

18 of 50

0 of 25

0.000315482

IGFN1

Patient

Normal

17 of 50

0 of 25

0.000375298

PABPC1

Patient

Normal

16 of 50

0 of 25

0.000728519

KRT79

Patient

Normal

9 of 50

0 of 25

0.02508378

FLNA

Patient

Normal

9 of 50

0 of 25

0.02508378

PHRF1

Patient

Normal

9 of 50

0 of 25

0.02508378

ALS2CL

Patient

Normal

10 of 50

0 of 25

0.025483837

KNSTRN

Patient

Normal

10 of 50

0 of 25

0.025483837

COL6A5

Patient

Normal

8 of 50

0 of 25

0.046170366

TSHZ2

Patient

Normal

8 of 50

0 of 25

0.046170366

AADAC

Patient

Normal

8 of 50

0 of 25

0.046170366

ADAT1

Patient

Normal

8 of 50

0 of 25

0.046170366

CMA1

Patient

Normal

8 of 50

0 of 25

0.046170366

DEAF1

Patient

Normal

8 of 50

0 of 25

0.046170366

DLAT

Patient

Normal

8 of 50

0 of 25

0.046170366

DST

Patient

Normal

8 of 50

0 of 25

0.046170366

FLG

Patient

Normal

8 of 50

0 of 25

0.046170366

KIAA0556

Patient

Normal

8 of 50

0 of 25

0.046170366

LPA

Patient

Normal

8 of 50

0 of 25

0.046170366

P2RX5

Patient

Normal

8 of 50

0 of 25

0.046170366

PANK2

Patient

Normal

8 of 50

0 of 25

0.046170366

RASSF4

Patient

Normal

8 of 50

0 of 25

0.046170366

WARS

Patient

Normal

8 of 50

0 of 25

0.046170366

ZNF572

Patient

Normal

8 of 50

0 of 25

0.046170366

  1. Frequency of allele mutations were zero in controls and FDR < 0.05