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Table 2 The association of MTNR1B SNPs with BMI and waist circumference

From: Association between MTNR1B polymorphisms and obesity in African American: findings from the Jackson Heart Study

     

BMI

Waist circumference

 

SNPs

BP

A1

A2

MAF

p value

FDR p value

Beta

SE (Beta)

p value

FDR p value

Beta

SE (Beta)

Type of Mutation

rs3781638

92980341

T

G

0.499

0.0041

0.0200

−0.0158

0.0055

0.0006

0.0075

−0.0140

0.0041

Intronic

rs1562444

92982683

A

G

0.446

0.0056

0.0200

−0.0153

0.0055

0.0007

0.0075

−0.0138

0.0041

3'-UTR

rs12792653

92982750

A

G

0.446

0.0056

0.0200

−0.0153

0.0055

0.0008

0.0075

−0.0138

0.0041

3'-UTR

rs8192552

92969796

G

A

0.094

0.0432

0.0925

0.0189

0.0094

0.0010

0.0077

0.0228

0.0069

Missense

rs6483209

92976223

C

T

0.212

0.0025

0.0200

−0.0201

0.0067

0.0020

0.0089

−0.0153

0.0050

Intronic

rs12290860

92979012

G

A

0.224

0.0060

0.0200

−0.0184

0.0067

0.0017

0.0089

−0.0155

0.0049

Intronic

rs7127128

92980510

A

G

0.227

0.0029

0.0200

−0.0196

0.0066

0.0024

0.0089

−0.0149

0.0049

Intronic

rs6483210

92981429

C

T

0.227

0.0029

0.0200

−0.0197

0.0066

0.0025

0.0089

−0.0148

0.0049

Intronic

rs61747139

92981951

A

G

0.227

0.0030

0.0200

−0.0196

0.0066

0.0027

0.0089

−0.0147

0.0049

Missense

rs10765576

92973778

G

A

0.489

0.0332

0.0831

−0.0117

0.0055

0.0038

0.0096

−0.0117

0.0040

Intronic

rs11020127

92974394

C

A

0.495

0.0050

0.0200

−0.0186

0.0067

0.0034

0.0096

−0.0119

0.0041

Intronic

rs12292400

92979446

G

C

0.225

0.0394

0.0909

−0.0112

0.0054

0.0038

0.0096

−0.0143

0.0049

Intronic

rs12272268

92975633

C

G

0.252

0.0184

0.0501

−0.0147

0.0063

0.0048

0.0111

−0.0131

0.0046

Intronic

rs7130424

92980527

T

C

0.266

0.0099

0.0298

−0.0160

0.0062

0.0054

0.0116

−0.0128

0.0046

Intronic

rs11020126

92973751

G

A

0.181

0.0606

0.1212

−0.0136

0.0072

0.0165

0.0331

−0.0129

0.0054

Intronic

rs11020125

92973378

T

G

0.171

0.0895

0.1679

−0.0124

0.0073

0.0218

0.0409

−0.0124

0.0054

Intronic

rs6483208

92972678

T

G

0.22

0.1446

0.2411

−0.0096

0.0066

0.0287

0.0507

−0.0107

0.0049

Intronic

  1. BMI for adjusted age, sex, and ancestry; Waist Circumference for adjusted age, sex, and ancestry. The associations' results are Beta, standard error (SE), and the corresponding adjusted False Discovery Rate (FDR) p value. A1 and A2 are reference allele and alternative allele; MAF is Minor Allele Frequency; BP is Base Pair