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Table 3 The Association between MTNR1B Variants and Adiposity adjusting for Insomnia

From: Association between MTNR1B polymorphisms and obesity in African American: findings from the Jackson Heart Study

      Adiposity Adiposity-Insomnia  
SNPs BP A1 A2 MAF p value FDR
p value
OR LCI UCI p value FDR
p value
OR LCI UCI Type of Mutation
rs12290860 92979012 G A 0.2240 0.0042 0.0250 0.74 0.54 0.95 0.0012 0.0040 0.66 0.40 0.91 Intronic
rs61747139 92981951 A G 0.2270 0.0042 0.0250 0.74 0.54 0.95 0.0013 0.0040 0.66 0.41 0.92 Missense
rs6483210 92981429 C T 0.2270 0.0043 0.0250 0.75 0.54 0.95 0.0013 0.0040 0.66 0.41 0.92 Intronic
rs7127128 92980510 A G 0.2270 0.0044 0.0250 0.75 0.54 0.95 0.0013 0.0040 0.66 0.41 0.92 Intronic
rs12292400 92979446 G C 0.2250 0.0055 0.0250 0.75 0.55 0.95 0.0017 0.0047 0.67 0.41 0.92 Intronic
rs6483209 92976223 C T 0.2120 0.0022 0.0250 0.73 0.52 0.93 0.0003 0.0025 0.62 0.36 0.88 Intronic
rs7130424 92980527 T C 0.2660 0.0117 0.0281 0.79 0.60 0.97 0.0021 0.0053 0.70 0.46 0.93 Intronic
rs12272268 92975633 C G 0.2520 0.0075 0.0250 0.77 0.58 0.96 0.0007 0.0040 0.67 0.43 0.91 Intronic
rs12792653 92982750 A G 0.4460 0.0121 0.0281 0.81 0.64 0.97 0.0872 0.1313 0.83 0.62 1.04 3’-UTR
rs1562444 92982683 A G 0.4460 0.0122 0.0281 0.81 0.64 0.98 0.0875 0.1313 0.83 0.62 1.04 3’-UTR
rs11020126 92973751 G A 0.1810 0.0060 0.0250 0.73 0.51 0.96 0.000045 0.0012 0.56 0.27 0.84 Intronic
rs11020125 92973378 T G 0.1710 0.0070 0.0250 0.74 0.51 0.96 0.0001 0.0012 0.57 0.28 0.86 Intronic
rs12277904 92978680 C T 0.1370 0.0105 0.0281 0.73 0.48 0.97 0.0115 0.0203 0.68 0.38 0.98 Intronic
rs116625623 92971729 G T 0.0950 0.0180 0.0385 0.70 0.41 1.00 0.0012 0.0040 0.54 0.17 0.92 Intronic
rs7129768 92980510 G A 0.0880 0.0202 0.0404 0.70 0.40 1.00 0.0033 0.0075 0.56 0.18 0.95 Intronic
rs76371840 92971529 C T 0.0740 0.0266 0.0499 1.48 1.13 1.82 0.0423 0.0705 1.54 1.12 1.96 Intronic
rs6483208 92972678 T G 0.2200 0.0291 0.0514 0.80 0.60 1.00 0.0003 0.0025 0.63 0.38 0.89 Intronic
rs4388843 92971820 G A 0.3110 0.2311 0.3015 0.90 0.72 1.08 0.0058 0.0123 0.73 0.50 0.95 Intronic
rs4601728 92971992 A G 0.3130 0.2432 0.3040 0.90 0.72 1.08 0.0066 0.0132 0.73 0.51 0.96 Intronic
rs12804291 92972141 C T 0.2650 0.2203 0.3005 0.89 0.71 1.08 0.0092 0.0172 0.73 0.50 0.97 Intronic
  1. Adiposity for adjusted age, sex, and ancestry; Adiposity-Insomnia for Adiposity model with adjustment for Insomnia. The results of the associations are listed as Odds Ratio (OR) with the Lower and Upper Confidence Interval (LCI and UCI) and the corresponding adjusted False Discovery Rate (FDR) p value. A1 and A2 are reference allele and alternative allele; MAF is Minor Allele Frequency; BP is Base Pair