Table 1 Summary of the exonic SNPs that undergo allelic selection in four cancer types
From: Exonic variants undergoing allele-specific selection in cancers
Significance level | Cancer type | Number of selected-for alleles | Number of genes affected by the selected-for alleles | Number of selected-against alleles | Number of genes affected by the selected-against alleles |
|---|---|---|---|---|---|
0.001 | BRCA | 31 | 31 | 64 | 60 |
LUAD | 36 | 33 | 116 | 112 | |
COAD | 21 | 21 | 22 | 22 | |
PRAD | 0 | 0 | 2 | 2 | |
0.01 | BRCA | 250 | 232 | 366 | 337 |
LUAD | 284 | 259 | 651 | 609 | |
COAD | 214 | 203 | 243 | 232 | |
PRAD | 4 | 3 | 29 | 29 | |
0.05 | BRCA | 1071 | 963 | 1605 | 1360 |
LUAD | 1080 | 945 | 2138 | 1770 | |
COAD | 1058 | 916 | 1207 | 1076 | |
PRAD | 101 | 95 | 278 | 259 |