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Table 2 Alleles undergoing significant somatic selection in cancers with q-value less than 0.1

From: Exonic variants undergoing allele-specific selection in cancers

Cancer Type RS id Gene Chromosome Position Ref Alt MAF Function \({\pi }_{i}\) P values
LUAD rs6790837 HEG1 chr3 124,732,618 A G 0.441 Nonsynonymous SNV 0.272 5.06E-06
rs35659744 MAP3K6 chr1 27,687,466 G T 0.122 Nonsynonymous SNV 0.293 1.01E-05
rs17851629 GTF2IRD1 chr7 73,932,560 A G 0.237 Synonymous SNV 0.297 1.39E-05
rs12683 MYDGF chr19 4,658,047 A G 0.166 Synonymous SNV 0.297 1.39E-05
rs4727323 PDK4 chr7 95,216,394 T G 0.459 Synonymous SNV 0.305 2.40E-05
rs17104362 RBM27 chr5 145,650,597 A G 0.162 Synonymous SNV 0.310 3.04E-05
rs73732050 C6orf89 chr6 36,867,376 C T 0.00579 Synonymous SNV 0.312 3.29E-05
rs1052690 IDNK chr9 86,258,685 A C 0.0972 Nonsynonymous SNV 0.316 4.93E-05
rs2233188 MLLT1 chr19 6,230,692 G A 0.0705 Synonymous SNV 0.317 4.93E-05
rs3730463 POLL chr10 103,344,589 T G 0.0583 Nonsynonymous SNV 0.319 5.44E-05
rs10401174 CNN1 chr19 11,660,538 G T 0.132 Synonymous SNV 0.320 6.20E-05
rs7865299 VAV2 chr9 136,662,928 A G 0.261 Synonymous SNV 0.321 6.58E-05
rs7820872 RAB11FIP1 chr8 37,728,019 T G 0.199 Synonymous SNV 0.322 6.70E-05
rs34546634 ACAN chr15 89,401,814 G A 0.0274 Nonsynonymous SNV 0.678 6.70E-05
rs12204826 RSPH3 chr6 159,398,803 C T 0.0142 Nonsynonymous SNV 0.680 6.20E-05
rs144579994 MCEMP1 chr19 7,743,399 C T 0.00539 Synonymous SNV 0.680 5.56E-05
rs138939062 TMEM184B chr22 38,617,704 G C 0.00799 Synonymous SNV 0.682 5.19E-05
rs140442228 TJP2 chr9 71,863,038 C T 0.00699 Synonymous SNV 0.683 5.19E-05
rs11996801 EPHX2 chr8 27,364,442 A C 0.0601 synonymous snv 0.686 4.55E-05
rs11788754 TJP2 chr9 71,861,685 G A 0.00699 Synonymous SNV 0.691 3.04E-05
rs11542503 SYT5 chr19 55,687,413 C T 0.0401 Nonsynonymous SNV 0.693 2.66E-05
BRCA rs61555831 SLCO2B1 chr11 74,907,721 C T 0.0727 Synonymous snv 0.705 1.02E-05
rs60209570 WSCD1 chr17 5,991,337 A C 0.025 Nonsynonymous SNV 0.292 8.88E-06
rs61739501 SMG6 chr17 2,203,225 C T 0.0118 Synonymous SNV 0.732 5.08E-06
rs201311722 TMEM161B chr5 87,516,503 A C 0.05 Nonsynonymous SNV 0.274 5.08E-06
rs200333134 DCDC2B chr1 32,674,703 T G 0.216 Synonymous SNV 0.282 5.08E-06