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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Identification of key genes in calcific aortic valve disease via weighted gene co-expression network analysis

Fig. 2

Identification of differentially expressed genes between calcified and normal aortic valve samples. Volcano plots of the differential gene expression data from a GSE83453, c GSE51472, and e GSE12644. In the volcano plots, the red points show up-regulated genes (log2FC ≥ 0.5 and adjusted P-value < 0.05), whereas the blue points represent down-regulated genes. Heatmap of the top 10 differentially expressed genes based on b GSE83453, d GSE51472, and f GSE12644. The color intensity (from red to blue) suggests the higher to lower expression. FC fold‐change

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