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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Identification of potential therapeutic targets for atherosclerosis by analysing the gene signature related to different immune cells and immune regulators in atheromatous plaques

Fig. 5

Comparison of the expression of genes related to different immune regulators in GSE100927. ns: p > 0.05, *p <  = 0.05, **p  ≤ 0.01, ***p  ≤ 0.001, ****p  ≤ 0.0001. 80 genes were detected in GSE100927. A–E were a set of comparisons between atheromatous plaques and healthy control: A box plot comparing the expression of human leukocyte antigen (HLA)-related genes, B immune checkpoint-related genes, C IFN-γ pathway marker genes, D m6A methylation regulator-related genes, E circadian rhythm-related genes. F–J were a set of comparisons between atheromatous plaques in the ImmuneScoreH cluster with that in atheromatous plaques in the ImmuneScoreL cluster: F Box plot comparing the expression of HLA-related genes, G immune checkpoint-related genes, H IFN-γ pathway marker genes, I m6A methylation regulator-related genes, J circadian rhythm-related genes. K Summarized the consistent results between the two sets of comparisons (atheromatous plaques vs. healthy controls/ImmunceScoreH cluster vs. ImmunceScoreL cluster)

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BMC Medical Genomics

ISSN: 1755-8794

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