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Table 2 General characteristic of T2DM and control group for validation study

From: Deregulation of lncRNA HIST1H2AG-6 and AIM1-3 in peripheral blood mononuclear cells is associated with newly diagnosed type 2 diabetes

Clinical characteristics T2DM (n = 100) control (n = 90) P value
Sex (male/female) 45/55 43/47 0.701
Age (years) 49.2 ± 12.2 46.5 ± 10.4 0.302
BMI (kg/m2) 24.2 (22.9–25.9) 20.8 (20.1–24.5) 0.047
DBP (mmHg) 78 (70–80) 73 (68–80) 0.124
SBP (mmHg) 138 (130–140) 130 (125–140) 0.003
WBC (× 109/L) 4.8 (4.4–5.7) 4.7 (4.5–5.8) 0.984
FPG (mmol/L) 10.7 (8.8–13.2) 5.3 (4.9–5.8) 0.000
HbA1c (%) 9.3 (8.0–11.5) 4.8 (4.4–5.1) 0.000
FINS (uIu/ml) 5.3 (3.7–8.3) 7.2 (6.7–8.7) 0.000
HOMA-B 11.7(6.5–24) 108.8(91.6–141.9) < 0.001
HOMA-IR 2.5(1.6–4.1) 1.6(1.4–2.0) < 0.001
TG (mmol/l) 1.7 (1.0–2.3) 1.2 (0.9–1.8) 0.278
LDL-C (mmol/l) 2.8 ± 0.8 2.5 ± 0.5 0.002
HDL-C (mmol/l) 1.1 ± 0.3 1.3 ± 0.3 0.000
UA (mmol/L) 336.1 ± 59.5 330.5 ± 79.5 0.576
  1. Data are expressed as mean ± standard deviation values, numbers, or medians (interquartile ranges). Data were analyzed using the unpaired Student’s t-test, x2-test and Mann–Whitney test, as appropriate
  2. BMI, body mass index; DBP, diastolic blood pressure; SBP, systolic blood pressure; WBC, white blood cell; FPG, fasting plasma glucose; HbA1c, haemoglobin A1c; FIN, fasting insulin; TG, triglyceride; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; UA, urine acid