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Table 5 The SNPs of STAT4 associated with T2D risk in the subgroup tests (BMI)

From: Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population

SNP ID Model Genotype OR (95% CI) p OR (95% CI) p
     ≤ 24  > 24
rs3821236 Allele A 1.30(0.95–1.79) 0.099 1.1(0.84–1.44) 0.498
   G 1.00   1.00  
  Genotype AA 1.82(0.94–3.53) 0.076 1.18(0.69–2.04) 0.544
   AG 1.35(0.81–2.24) 0.250 1.17(0.73–1.87) 0.505
   GG 1.00   1.00  
  Dominant AA-AG 1.46(0.90–2.36) 0.123 1.18(0.76–1.82) 0.470
   GG 1.00   1.00  
  Recessive AA 1.51(0.85–2.71) 0.164 1.07(0.68–1.68) 0.778
   AG-GG 1.00   1.00  
  Log-additive 1.35(0.98–1.87) 0.070 1.09(0.83–1.43) 0.538
rs11893432 Allele G 1.34(0.98–1.84) 0.066 1.03(0.79–1.35) 0.830
   C 1.00   1.00  
  Genotype GG 1.83(0.95–3.52) 0.070 1.07(0.62–1.84) 0.815
   GC 1.51(0.91–2.52) 0.113 0.88(0.55–1.42) 0.609
   CC 1.00   1.00  
  Dominant GG-GC 1.59(0.98–2.58) 0.059 0.94(0.60–1.47) 0.792
   CC 1.00   1.00  
  Recessive GG 1.42(0.80–2.51) 0.236 1.16(0.74–1.81) 0.521
   GC-CC 1.00   1.00  
  Log-additive 1.37(0.99–1.90) 0.055 1.03(0.79–1.36) 0.818
rs11889341 Allele T 1.41(1.01–1.98) 0.115 1.86(0.65–2.14) 0.282
   C 1.00   1.00  
  Genotype TT 1.62(0.72–3.63) 0.243 1.73(1.38–2.41) 0.353
   TC 1.63(1.02–2.62) 0.143 1.29(0.52–2.21) 0.279
   CC 1.00   1.00  
  Dominant TT-TC 1.63(1.04–2.56) 0.035* 1.78(0.52–2.17) 0.230
   CC 1.00   1.00  
  Recessive TT 1.27(0.58–2.75) 0.549 1.84(0.45–2.54) 0.564
   TC-CC 1.00   1.00  
  Log-additive 1.41(0.99–2.00) 0.059 1.84(0.62–2.33) 0.239
rs7574865 Allele T 1.36(0.97–1.91) 0.073 1.37(0.66–2.16) 0.342
   G 1.00   1.00  
  Genotype TT 1.26(0.58–2.74) 0.555 1.48(0.39–2.15) 0.483
   TG 1.75(1.09–2.83) 0.021* 1.80(0.53–2.21) 0.288
   GG 1.00   1.00  
  Dominant TT-TG 1.65(1.05–2.59) 0.030* 1.28(0.53–1.99) 0.263
   GG 1.00   1.00  
  Recessive TT 0.96(0.46–2.03) 0.921 1.19(0.47–1.89) 0.721
   TG-GG 1.00   1.00  
  Log-additive 1.33(0.94–1.89) 0.108 1.65(0.63–2.26) 0.306
rs897200 Allele C 0.83(0.60–1.13) 0.229 1.16(0.89–1.52) 0.274
   T 1.00   1.00  
  Genotype CC 0.66(0.34–1.27) 0.214 1.33(0.78–2.26) 0.294
   CT 1.20(0.71–2.03) 0.503 0.86(0.53–1.39) 0.538
   TT 1.00   1.00  
  Dominant CC-CT 1.02(0.62–1.68) 0.944 1.02(0.65–1.59) 0.933
   TT 1.00   1.00  
  Recessive CC 0.59(0.34–1.02) 0.059 1.46(0.95–2.25) 0.085
   CT-TT 1.00   1.00  
  Log-additive 0.84(0.60–1.16) 0.287 1.16(0.89–1.51) 0.266
  1. BMI body mass index, CI confidence interval, OR odds ratio
  2. p: values were calculated by unconditional logistic regression analysis with adjustment for age and gender, *p < 0.05 indicates statistical significance