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Table 5 The SNPs of STAT4 associated with T2D risk in the subgroup tests (BMI)

From: Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population

SNP ID

Model

Genotype

OR (95% CI)

p

OR (95% CI)

p

   

 ≤ 24

 > 24

rs3821236

Allele

A

1.30(0.95–1.79)

0.099

1.1(0.84–1.44)

0.498

  

G

1.00

 

1.00

 
 

Genotype

AA

1.82(0.94–3.53)

0.076

1.18(0.69–2.04)

0.544

  

AG

1.35(0.81–2.24)

0.250

1.17(0.73–1.87)

0.505

  

GG

1.00

 

1.00

 
 

Dominant

AA-AG

1.46(0.90–2.36)

0.123

1.18(0.76–1.82)

0.470

  

GG

1.00

 

1.00

 
 

Recessive

AA

1.51(0.85–2.71)

0.164

1.07(0.68–1.68)

0.778

  

AG-GG

1.00

 

1.00

 
 

Log-additive

1.35(0.98–1.87)

0.070

1.09(0.83–1.43)

0.538

rs11893432

Allele

G

1.34(0.98–1.84)

0.066

1.03(0.79–1.35)

0.830

  

C

1.00

 

1.00

 
 

Genotype

GG

1.83(0.95–3.52)

0.070

1.07(0.62–1.84)

0.815

  

GC

1.51(0.91–2.52)

0.113

0.88(0.55–1.42)

0.609

  

CC

1.00

 

1.00

 
 

Dominant

GG-GC

1.59(0.98–2.58)

0.059

0.94(0.60–1.47)

0.792

  

CC

1.00

 

1.00

 
 

Recessive

GG

1.42(0.80–2.51)

0.236

1.16(0.74–1.81)

0.521

  

GC-CC

1.00

 

1.00

 
 

Log-additive

1.37(0.99–1.90)

0.055

1.03(0.79–1.36)

0.818

rs11889341

Allele

T

1.41(1.01–1.98)

0.115

1.86(0.65–2.14)

0.282

  

C

1.00

 

1.00

 
 

Genotype

TT

1.62(0.72–3.63)

0.243

1.73(1.38–2.41)

0.353

  

TC

1.63(1.02–2.62)

0.143

1.29(0.52–2.21)

0.279

  

CC

1.00

 

1.00

 
 

Dominant

TT-TC

1.63(1.04–2.56)

0.035*

1.78(0.52–2.17)

0.230

  

CC

1.00

 

1.00

 
 

Recessive

TT

1.27(0.58–2.75)

0.549

1.84(0.45–2.54)

0.564

  

TC-CC

1.00

 

1.00

 
 

Log-additive

1.41(0.99–2.00)

0.059

1.84(0.62–2.33)

0.239

rs7574865

Allele

T

1.36(0.97–1.91)

0.073

1.37(0.66–2.16)

0.342

  

G

1.00

 

1.00

 
 

Genotype

TT

1.26(0.58–2.74)

0.555

1.48(0.39–2.15)

0.483

  

TG

1.75(1.09–2.83)

0.021*

1.80(0.53–2.21)

0.288

  

GG

1.00

 

1.00

 
 

Dominant

TT-TG

1.65(1.05–2.59)

0.030*

1.28(0.53–1.99)

0.263

  

GG

1.00

 

1.00

 
 

Recessive

TT

0.96(0.46–2.03)

0.921

1.19(0.47–1.89)

0.721

  

TG-GG

1.00

 

1.00

 
 

Log-additive

1.33(0.94–1.89)

0.108

1.65(0.63–2.26)

0.306

rs897200

Allele

C

0.83(0.60–1.13)

0.229

1.16(0.89–1.52)

0.274

  

T

1.00

 

1.00

 
 

Genotype

CC

0.66(0.34–1.27)

0.214

1.33(0.78–2.26)

0.294

  

CT

1.20(0.71–2.03)

0.503

0.86(0.53–1.39)

0.538

  

TT

1.00

 

1.00

 
 

Dominant

CC-CT

1.02(0.62–1.68)

0.944

1.02(0.65–1.59)

0.933

  

TT

1.00

 

1.00

 
 

Recessive

CC

0.59(0.34–1.02)

0.059

1.46(0.95–2.25)

0.085

  

CT-TT

1.00

 

1.00

 
 

Log-additive

0.84(0.60–1.16)

0.287

1.16(0.89–1.51)

0.266

  1. BMI body mass index, CI confidence interval, OR odds ratio
  2. p: values were calculated by unconditional logistic regression analysis with adjustment for age and gender, *p < 0.05 indicates statistical significance