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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia

Fig. 2

Repeat element expression in Blueprint AML data sets. a Fraction of repeat transcripts (blue) versus protein coding transcripts (green) in the HSC (n = 3), MPP (n = 3) and CMP (n = 3) CD34 + cell populations. b Fraction of repeat transcripts for distinct repeat classes in HSC, MPP and CMP samples. Error bars represent the standard of the mean (SEM). c MA-plots (mean expression versus the log2 fold change) comparing CD34 + control (n = 9) versus AML patient samples (n = 14). Dots above and below the dashed lines are statistically significant as confirmed by multiple testing adjustments using the BH (Benjamini–Hochberg) method. Some examples for de-repressed Satellite repeats and LTR/ERV elements are highlighted. Red dots represent Satellite repeats, blue dots LTR/ERV elements and orange dots LINE repeats

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