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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia

Fig. 3

R/G ratios can stratify AML patient subgroups. a Fraction of repeat transcripts (blue) versus fraction of protein coding transcripts (green) in TCGA AML patient samples. Within each M1 (n = 35), M2 (n = 35) and M4 (n = 28) AML subtype, patient samples are ordered according to increasing fraction of repeat transcripts. b Table showing the number of patient samples in each cohort (Uniklinik Freiburg AML, Blueprint AML and TCGA AML) that were classified by R/G ratio in High-repeat, Mid-repeat and Low-repeat subgroups. c MA-plots (mean expression versus the log2 fold change) depicting changes in repeat expression in the High-repeat (n = 16) versus Mid-repeat (n = 89) and in the Low-repeat (n = 15) versus Mid-repeat (n = 89) AML patient samples. x-axis indicates the baseMean values and y-axis the log2 fold change values (DESeq2). Dots above and below the dashed lines are statistically significant as confirmed by multiple testing adjustments using the BH (Benjamini–Hochberg) method

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