|
Parameters
|
MTNR1B rs10830963 genotype
|
P value
|
|---|
|
CC
|
CG
|
GG
|
|---|
|
N (men/women)
|
70(40/30)
|
90(48/42)
|
40(23/17)
|
0.850Δ
|
|
Age (years)
|
47.81 ± 10.82
|
48.01 ± 12.04
|
47.09 ± 13.92
|
0.921
|
|
BMI (kg/m2)
|
26.41 ± 3.24
|
25.43 ± 3.31
|
26.59 ± 4.11
|
0.104
|
|
WHR
|
0.92 ± 0.06
|
0.91 ± 0.06
|
0.92 ± 0.08
|
0.552#
|
|
FPG (mmol/L)
|
9.61 ± 2.01
|
9.91 ± 2.79
|
10.82 ± 1.79
|
0.034*
|
|
PPG (mmol/L)
|
15.36 ± 2.46
|
14.21 ± 4.39
|
14.69 ± 5.71
|
0.224
|
|
FINS (mU/L)
|
8.56 ± 5.39
|
7.37 ± 6.99
|
7.53 ± 6.39
|
0.477#
|
|
PINS (mU/L)
|
30.01 ± 17.10
|
28.11 ± 20.51
|
33.51 ± 17.49
|
0.320
|
|
HOMA-IR
|
3.27 ± 1.30
|
3.09 ± 3.21
|
4.01 ± 2.47
|
0.160
|
|
HbA1c (%)
|
9.71 ± 1.97
|
9.11 ± 2.62
|
9.95 ± 2.04
|
0.098
|
|
TG (mmol/L)
|
2.25 ± 1.38
|
2.31 ± 2.13
|
1.97 ± 1.52
|
0.596
|
|
TC (mmol/L)
|
5.21 ± 1.29
|
4.99 ± 1.31
|
5.49 ± 1.51
|
0.143
|
|
HDL-c (mmol/L)
|
1.28 ± 0.95
|
1.33 ± 0.59
|
1.41 ± 0.29
|
0.645
|
|
LDL-c (mmol/L)
|
3.45 ± 0.68
|
3.61 ± 1.19
|
3.80 ± 0.93
|
0.199#
|
- BMI body mass index, WHR waist to hip ratio, FPG fasting plasma glucose, PPG postprandial plasma glucose, FINS fasting serum insulin, PINS postprandial serum insulin, HOMA-IR homeostasis model assessment for insulin resistance, HbA1c hemoglobin A1c, TG triglyceride, TC total cholesterol, HDL-c high-density lipoprotein-cholesterol, LDL-c low-density lipoprotein-cholesterol
- Data are given as (mean ± SD). P values represent statistical differences among the three different genotypes by the one-way ANOVA. ΔP values are determined by the Pearson chi-square test. #P values are determined by the Kruskal–Wallis test. *P < 0.05
