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Table 1 IA risk associated SNPs and the associated linkage disequilibrium blocks

From: Epigenetic landscapes of intracranial aneurysm risk haplotypes implicate enhancer function of endothelial cells and fibroblasts in dysregulated gene expression

Sentinel SNP SNP Location Nearest Gene LD Block (hg38) Length (bp)
rs3767137 Intronic HSPG2 chr1:21834230–21841817 7587
rs1800255 Exonic COL3A1 chr2:188976887–189003156 26,269
rs1429412 Intergenic ANKRD44 chr2:197283467–197358397 74,930
rs700651 Intronic BOLL chr2:197676674–197766990 90,316
rs6841581 Intergenic EDNRA chr4:147444187–147493499 49,312
rs251124 Intronic VCAN chr5:83509605–83530435 20,830
rs4628172 Intronic AGMO chr7:15454259–15466904 12,645
rs1800796 Intronic IL6 chr7:22726627–22732119 5492
rs42524 Exonic COL1A2 chr7:94413927–94420044 6117
rs10958409 Intergenic chr8:54397171–54415556 18,385
rs9298506 Intergenic chr8:54509054–54549764 40,710
rs2891168 Intronic CDKN2B-AS1 chr9:22072265–22125504 53,239
rs10757278 Intergenic CDKN2B-AS1 chr9:22077086–22125504 48,418
rs6538595 Intronic FGD6 chr12:95095355–95123067 27,712
rs4934 Exonic SERPINA3 chr14:94612340–94614466 2126
rs1132274 Exonic RRBP1 chr20:17613385–17619469 6084
  1. Bolded SNPs were chosen as examples in Fig. 1, Fig. 2, and Additional file 1: Fig. S1
  2. hg, human genome; IA, intracranial aneurysm; rs, reference SNP cluster ID; SNP, single nucleotide polymorphism; chr, chromosome; LD, linkage disequilibrium