Fig. 5

Conformity of the observed effect of combining different genotypes at the MHC and two susceptibility regions with an additive and a multiplicative model of combined risk. The non-MHC susceptibility haplotypes are: (d1); (d2); and (d3)—see “Methods” section. The ORs listed are those actually observed (Figs. 4, 5). Only haplotype combinations with ≥ 15 or more representations in the WTCCC are shown. Combinations with fewer than 50 representations are shaded in pink; combinations with at least 50 representations are shaded in green