Fig. 1
From: Familial SYN1 variants related neurodevelopmental disorders in Asian pediatric patients
Two Asian patients with maternal inherited SYN1 variants. The above two figures (a, b) show the segregation of the SYN1 variants in the two pedigrees. a Pedigree A and b pedigree B:
, female carrier;
, affected male; arrow, the proband;
, induced abortion;
, spontaneous abortion. The middle two figures (c, d) show electropherograms of SYN1 genomic sequences of the two pedigrees. The represented DNA sequences is in positive strand. e The alignment of the SynI protein sequence across species. The mutated amino acids are marked in red color, and lay in conserved positions as indicated