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Table 6 Top ten enriched biological processes among target genes of miR-3163

From: The expression of miR-513c and miR-3163 was downregulated in tumor tissues compared with normal adjacent tissue of patients with breast cancer

No Gene set Biological pathways C E R FDR p value
1 GO: 0045934 Negative regulation of nucleobase-containing compound metabolic process 1418 22.805 1.9732 0.04352 8E−06
2 GO: 0033554 Cellular response to stress 1867 30.026 1.7984 0.04352 1E−05
3 GO: 0010629 Negative regulation of gene expression 1733 27.871 1.8299 0.04352 1E−05
4 GO: 1903311 Regulation of mRNA metabolic process 266 4.278 3.5063 0.06326 3E−05
5 GO: 0045935 Positive regulation of nucleobase-containing compound metabolic process 1847 29.705 1.7169 0.12664 8E−05
6 GO: 0000278 Mitotic cell cycle 927 14.909 2.0793 0.12664 9E−05
7 GO: 0051253 Negative regulation of RNA metabolic process 1295 20.827 1.8726 0.12664 1E−04
8 GO: 0000902 Cell morphogenesis 982 15.793 2.0262 0.12664 1E−04
9 GO: 0032989 Cellular component morphogenesis 1082 17.401 1.9539 0.12664 1E−04
10 GO: 2000113 Negative regulation of cellular macromolecule biosynthetic process 1359 21.856 1.8301 0.12664 1E−04