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Table 6 Top ten enriched biological processes among target genes of miR-3163

From: The expression of miR-513c and miR-3163 was downregulated in tumor tissues compared with normal adjacent tissue of patients with breast cancer

No

Gene set

Biological pathways

C

E

R

FDR

p value

1

GO: 0045934

Negative regulation of nucleobase-containing compound metabolic process

1418

22.805

1.9732

0.04352

8E−06

2

GO: 0033554

Cellular response to stress

1867

30.026

1.7984

0.04352

1E−05

3

GO: 0010629

Negative regulation of gene expression

1733

27.871

1.8299

0.04352

1E−05

4

GO: 1903311

Regulation of mRNA metabolic process

266

4.278

3.5063

0.06326

3E−05

5

GO: 0045935

Positive regulation of nucleobase-containing compound metabolic process

1847

29.705

1.7169

0.12664

8E−05

6

GO: 0000278

Mitotic cell cycle

927

14.909

2.0793

0.12664

9E−05

7

GO: 0051253

Negative regulation of RNA metabolic process

1295

20.827

1.8726

0.12664

1E−04

8

GO: 0000902

Cell morphogenesis

982

15.793

2.0262

0.12664

1E−04

9

GO: 0032989

Cellular component morphogenesis

1082

17.401

1.9539

0.12664

1E−04

10

GO: 2000113

Negative regulation of cellular macromolecule biosynthetic process

1359

21.856

1.8301

0.12664

1E−04