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Table 1 Type of genetic abnormalities

From: Retinoblastoma genetics screening and clinical management

S. nos. Genetic abnormality Number of mutations Number of patients Component of novel mutation No of pts with novel mutation Unilateral /bilateral
1 Whole gene deletion NA 4 NA NA 1:3
2 Missense mutation 7 7 2 2 3:4
3 Frame shift 1 1 NIL NIL 0:1
4 Splice site 3 4 1 1 0:4
5 Non-SENSE 10 13 NIL NIL 0:13
Total   19 29 3 7 4:25