Table 3 Correlating mutation versus clinical disease severity
From: Retinoblastoma genetics screening and clinical management
| Â | Splice site mutation | Missenese mutation | Termination | Whole gene deletion |
|---|---|---|---|---|
Total | 4 | 7 | 14 | 4 |
U:B | 0:04 | 3:04 | 0:14 | 1:03 |
Age (years) | 1.45 | 1.81 | 1.28 | 4.09 |
Enucleation | 4Â (100%) | 7Â (100%) | 10Â (71.4%) | 3 (75%) |
Average age at enucleation (years) | 1.83 | 1.95 | 2.02 | 1.98 * |
Avg pathological TNM | 2.6 | 2.14 | 1.85 | 2.3 |
Avg clinical TNM | 3.3 | 2.7 | 2.38 | 2.75 |