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Table 5 The association between PDX1 polymorphisms and the risk of T2DM stratified by BMI

From: PDX1 and MC4R genetic polymorphisms are associated with type 2 diabetes mellitus risk in the Chinese Han population

Gene SIP Model Genotype ≤ 24 > 24
OR (95% CI) p OR (95% CI) p
PDX1
rs7981781
Allele G 1.00   1.00  
A 1.07 (0.78–1.46) 0.675 0.94 (0.72–1.24) 0.682
Codominant GG 1.00   1.00  
AA 1.10 (0.59–2.06) 0.766 0.97 (0.54–1.72) 0.910
AG 0.98 (0.58–1.64) 0.928 0.64 (0.41–1.00) 0.049
Dominant GG 1.00   1.00  
AA-AG 1.01 (0.62–1.65) 0.956 0.72 (0.47–1.09) 0.117
Recessive AG-GG 1.00   1.00  
AA 1.12 (0.65–1.92) 0.690 1.26 (0.75–2.10) 0.383
Additive 1.04 (0.76–1.43) 0.790 0.92 (0.70–1.22) 0.559
  1. SNP single nucleotide polymorphism, OR odds ratio, 95% CI 95% confidence interval
  2. p values were calculated by logistic regression analysis with adjustment for age and gender
  3. Bold values indicate statistical significance (p < 0.05)