Table 5 The association between PDX1 polymorphisms and the risk of T2DM stratified by BMI
Gene SIP | Model | Genotype | ≤ 24 | > 24 | ||
|---|---|---|---|---|---|---|
OR (95% CI) | p | OR (95% CI) | p | |||
PDX1 rs7981781 | Allele | G | 1.00 | 1.00 | ||
A | 1.07 (0.78–1.46) | 0.675 | 0.94 (0.72–1.24) | 0.682 | ||
Codominant | GG | 1.00 | 1.00 | |||
AA | 1.10 (0.59–2.06) | 0.766 | 0.97 (0.54–1.72) | 0.910 | ||
AG | 0.98 (0.58–1.64) | 0.928 | 0.64 (0.41–1.00) | 0.049 | ||
Dominant | GG | 1.00 | 1.00 | |||
AA-AG | 1.01 (0.62–1.65) | 0.956 | 0.72 (0.47–1.09) | 0.117 | ||
Recessive | AG-GG | 1.00 | 1.00 | |||
AA | 1.12 (0.65–1.92) | 0.690 | 1.26 (0.75–2.10) | 0.383 | ||
Additive | – | 1.04 (0.76–1.43) | 0.790 | 0.92 (0.70–1.22) | 0.559 | |