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Table 1 Clinical and biochemical data

From: A novel compound heterozygous variant of the SLC12A3 gene in Gitelman syndrome with diabetes and the choices of the appropriate hypoglycemic drugs: a case report

Clinical data

Normal range

Results

Serum potassium (mmol/L)

3.50–5.50

2.84

Serum sodium (mmol/L)

137.00–147.00

135.00

Serum chlorine (mmol/L)

99.00–110.00

87.44

Serum calcium (mmol/L)

2.11–2.52

2.06

Serum magnesium (mmol/L)

0.80–1.00

0.36

Fasting plasma glucose (mmol/L)

3.9–6.1

6.84

Serum pH

7.35–7.45

7.50

HCO3 (mmol/L)

21.0–28.0

34.30

Renin (ng/ml/h)

0.1–2.9

4.8

Aldosterone (pg/ml)

29.0–161.0

298.2

Urine potassium (mmol/24 h)

25.00–125.00

41.44

Urine sodium (mmol/24 h)

130.00–260.00

79.20

Urine chlorine (mmol/24 h)

170.00–255.00

90.89

Urine calcium (mmol/24 h)

2.50–7.50

0.10

Creatinine (μmol/24 h)

7000–18,000

2454

Fea potassium (%)

8.0–12.0

39.8

Fea sodium (%)

 < 1.0

1.6

Fea chlorine (%)

 < 1.0

2.8

Fea magnesium (%)

 < 4.0

33.1

Urine pH

4.6–8.0

8.0

Uric Acid (μmol/L)

89.2–339

142.00

Cholesterol (mmol/L)

2.32–5.62

2.32

Triglyceride (mmol/L)

0.30–1.92

2.67

High-density lipoprotein (mmol/L)

0.80–2.35

0.97

Low-density lipoprotein (mmol/L)

1.90–3.12

2.56

OGTT values

  

HOMA-βb (first) (100%)

100

42.8

HOMA-βb (second) (100%)

100

55.1

HOMA-IRc (first)

1

4.99

HOMA-IRc (second)

1

3.26

  1. Fea: fractional excretion of potassium, sodium, chlorine
  2. HOMA-βb = (20 × Ins 0, mIU/L)/(Gluc 0, mmol/L − 3.5) (%)
  3. HOMA-IRc = (Gluc 0 mmol/L × Ins 0, mIU/L)/22.5