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Table 1 Clinical and biochemical data

From: A novel compound heterozygous variant of the SLC12A3 gene in Gitelman syndrome with diabetes and the choices of the appropriate hypoglycemic drugs: a case report

Clinical data Normal range Results
Serum potassium (mmol/L) 3.50–5.50 2.84
Serum sodium (mmol/L) 137.00–147.00 135.00
Serum chlorine (mmol/L) 99.00–110.00 87.44
Serum calcium (mmol/L) 2.11–2.52 2.06
Serum magnesium (mmol/L) 0.80–1.00 0.36
Fasting plasma glucose (mmol/L) 3.9–6.1 6.84
Serum pH 7.35–7.45 7.50
HCO3 (mmol/L) 21.0–28.0 34.30
Renin (ng/ml/h) 0.1–2.9 4.8
Aldosterone (pg/ml) 29.0–161.0 298.2
Urine potassium (mmol/24 h) 25.00–125.00 41.44
Urine sodium (mmol/24 h) 130.00–260.00 79.20
Urine chlorine (mmol/24 h) 170.00–255.00 90.89
Urine calcium (mmol/24 h) 2.50–7.50 0.10
Creatinine (μmol/24 h) 7000–18,000 2454
Fea potassium (%) 8.0–12.0 39.8
Fea sodium (%)  < 1.0 1.6
Fea chlorine (%)  < 1.0 2.8
Fea magnesium (%)  < 4.0 33.1
Urine pH 4.6–8.0 8.0
Uric Acid (μmol/L) 89.2–339 142.00
Cholesterol (mmol/L) 2.32–5.62 2.32
Triglyceride (mmol/L) 0.30–1.92 2.67
High-density lipoprotein (mmol/L) 0.80–2.35 0.97
Low-density lipoprotein (mmol/L) 1.90–3.12 2.56
OGTT values   
HOMA-βb (first) (100%) 100 42.8
HOMA-βb (second) (100%) 100 55.1
HOMA-IRc (first) 1 4.99
HOMA-IRc (second) 1 3.26
  1. Fea: fractional excretion of potassium, sodium, chlorine
  2. HOMA-βb = (20 × Ins 0, mIU/L)/(Gluc 0, mmol/L − 3.5) (%)
  3. HOMA-IRc = (Gluc 0 mmol/L × Ins 0, mIU/L)/22.5