Table 2 The cox regression survival analysis in the entire group of patients (n = 256)
Factors | OS (n = 256) | PFS (n = 256) | ||
|---|---|---|---|---|
HR (95%CI) | p value | HR (95%CI) | p value | |
Gender | 2.010 (0.875–4.616) | 1.000 | 1.881 (0.816–4.334) | 0.138 |
Smoking | 3.975 (1.565–10.079) | 0.004 | 4.205 (1.645–10.752) | 0.003 |
Drinking | 0.281 (0.090–0.885) | 0.030 | 0.299 (0.095–0.943) | 0.039 |
TNM Stage | 0.246 (0.102–0.595) | 0.002 | 0.253 (0.105–0.607) | 0.002 |
Depth of tumor invasion | 0.623 (0.077–5.076) | 0.659 | 0.600 (0.073–4.900) | 0.634 |
Lymph node involvement | a | a | a | a |
Presence of metastasis | a | a | a | a |
Pathological type | 0.960 (0.327–2.818) | 0.940 | 0.905 (0.306–2.675) | 0.857 |
Chemotherapy | 0.240 (0.106–0.547) | 0.001 | 0.215 (0.092–0.502) |  < 0.001 |
D17S250 (MSI) | 1.494 (0.448–4.983) | 0.514 | 1.248 (0.372–4.186) | 0.719 |
MSH2-15 (MSI) | 7.701 (1.039–57.030) | 0.043 | 11.240 (1.992–63.410) | 0.006 |
pinch-5 (MSI) | 0.426 (0.023–7.987) | 0.569 | – | – |
MCC-25 (MSI) | – | – | 0.056 (0.002–1.628) | 0.094 |
MCC-10 (MSI) | 8.845 (0.610–128.268) | 0.110 | 31.851 (2.546–398.477) | 0.007 |