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Table 4 MSEA pathway analysis of the differential metabolites enriched

From: Untargeted metabolomic approach to study the serum metabolites in women with polycystic ovary syndrome

Metabolite set

Total

Hits

FDR

Purine metabolism

65

4

0.000000

Porphyrin and chlorophyll metabolism

30

3

0.000186

Taurine and hypotaurine metabolism

8

1

0.016056

Fatty acid degradation

39

1

0.040924

Phenylalanine metabolism

10

2

0.044818

Phenylalanine, tyrosine and tryptophan biosynthesis

4

2

0.044818

Fatty acid biosynthesis

47

1

0.070722

Primary bile acid biosynthesis

46

3

0.040924

Cysteine and methionine metabolism

33

3

0.050999

Pentose and glucuronate interconversions

18

1

0.205370

Valine, leucine and isoleucine degradation

40

3

0.205370

Sphingolipid metabolism

21

5

0.205370

Glutathione metabolism

28

2

0.205370

Arginine biosynthesis

14

3

0.205370

Valine, leucine and isoleucine biosynthesis

8

4

0.208410

Arginine and proline metabolism

38

4

0.205370

Beta-Alanine metabolism

21

2

0.249570

Steroid hormone biosynthesis

85

3

0.252260

Selenocompound metabolism

20

1

0.480370

Aminoacyl-tRNA biosynthesis

48

17

0.443750

Caffeine metabolism

10

2

0.480370

Pantothenate and CoA biosynthesis

19

1

0.534600

Alanine, aspartate and glutamate metabolism

28

3

0.648530

Alpha-Linolenic acid metabolism

13

1

0.648530

Tryptophan metabolism

41

4

0.780710

Ubiquinone and other terpenoid-quinone biosynthesis

9

1

0.649670

Tyrosine metabolism

42

1

0.649670

Glycine, serine and threonine metabolism

33

5

0.863790

Glyoxylate and dicarboxylate metabolism

32

3

0.803010

Pyrimidine metabolism

39

2

0.803010

Glycerophospholipid metabolism

36

1

0.788010

Butanoate metabolism

15

1

0.803010

Pentose phosphate pathway

22

1

0.803010

d-Glutamine and d-glutamate metabolism

6

1

0.824110

Nitrogen metabolism

6

1

0.824110

Lysine degradation

25

2

0.943180

Biotin metabolism

10

1

0.869120

Nicotinate and nicotinamide metabolism

15

1

0.943180

Histidine metabolism

16

1

0.959140

Galactose metabolism

27

1

0.959140

Glycerolipid metabolism

16

1

0.959140