Table 1 Patient demographics: discovery cohort

N per group

48

48

Age (years)

57.5

1.49

62.5

1.41

Race (% minority)

62.5

45.8

Sex (% male)

45.8

56.2

BMI

34.7

1.32

31.4

0.97

Current smoker (%)

8.3

14.6

Hypertension (%)

70.8

75.0

Systolic BP

135.85

3.02

137.05

3.80

Diastolic BP

72.67

1.66

72.67

1.83

Dyslipidemia (%)

58.3

70.8

Total Chol. (mg/dL)

180.50

4.80

167.09

4.91

LDL Chol. (mg/dL)

109.00

4.49

95.64

4.74

VLDL Chol. (mg/dL)

13.00

0.61

23.45

1.60

HDL Chol

51.00

0.61

47.82

1.40

Tri-glycerides

66.00

3.06

117.45

7.97

Creatine kinase-(U/L)

152.00

19.60

172.75

19.78

Diabetes (%)

35.4

33.3

Aspirin (%)

52.1

62.5

PTT (s)

29.77

0.60

30.96

0.67

PT (s)

12.97

0.24

13.13

0.41

INR

0.99

0.02

0.96

0.01

WBC (× 10³/uL)

6.99

0.35

6.92

0.36

RBC (× 10⁶/uL)

4.63

0.07

4.37

0.07

Hemoglobin (g/dL)

13.19

0.17

13.16

0.24

Hematocrit (%)

39.79

0.48

39.02

0.62

MCV (fL)

85.94

0.75

89.01

0.69

MCH (pg)

28.45

0.30

30.00

0.26

MCHC (g/dL)

33.06

0.17

33.70

0.18

RDW (%)

14.16

0.25

13.03

0.27

Platelet Count (× 10³/uL)

249.81

8.08

228.98

8.84

MPV (fL)

10.63

0.13

10.57

0.14

Seg. neutrophils (%)

56.34

1.83

62.30

1.59

Lymphocyte %

32.76

1.74

26.21

1.38

Eosinophil %

2.34

0.19

2.33

0.26

Basophil %

0.40

0.07

0.24

0.07

Abs. seg. neutrophils (× 10³/uL)

4.08

0.24

4.53

0.32

Abs. lymphocytes (× 10³/uL)

2.42

0.25

1.72

0.09

Abs. eosinophils (× 10³/uL)

0.16

0.01

0.16

0.02

Absolute basophils (× 10³/uL)

0.04

0.00

0.03

0.00

Auto monocyte %

7.53

0.34

8.35

0.39

Auto monocyte # (× 10³/uL)

0.53

0.03

0.56

0.03

Immature granulocytes %

0.24

0.02

0.25

0.02

RNA yield (ng/ul) 50 ul total

121.72

11.1113

96.48

7.50

Yield (ug/2.5 ml tube)

6.09

4.82

Total RNAseq reads

6.08E+07

4,189,732

5.35E+07

3,691,059

Filtered reads

2.44E+07

1,876,258

2.02E+07

1,522,361

Aligned reads (informative)

8.75E+06

773,714

6.65E+06

474,229.5