The effect of CYP7B1 polymorphisms on the risk of coronary heart disease in Hainan Han population

BMC Medical Genomics

Table 1 Basic characteristics of CHD patients and controls

Characteristics	Cases (n = 508)	Controls (n = 510)	p
Age, years (mean ± SD)^a	62.17 ± 10.34	61.12 ± 9.02	0.084
> 60	282 (55.5%)	284 (55.7%)
≤ 60	226 (45.5%)	226 (44.3%)
Gender ^b			0.964
Male	334 (65.7%)	336 (65.9%)
Female	174 (34.3%)	174 (34.1%)
Urea (mmol/l)^c	462.01 ± 4.50	456.63 ± 2.67	0.759
Creatinine (umol/l)^c	384.73 ± 3.40	456.07 ± 3.50	< 0.001
Uric acid (umol/l)^c	431.26 ± 1.08	489.10 ± 2.07	< 0.001
Total-cholesterol (mmol/l)^c	369.60 ± 1.00	548.04 ± 1.05	< 0.001
Apolipoprotein AI (g/l)^c	247.13 ± 5.74	351.08 ± 0.70	< 0.001
Smoking status
Smoker	231 (45.5%)	115 (22.5%)
Nonsmoker	186 (36.6%)	167 (32.7%)
Missing	91 (17.9%)	228 (44.8%)
Drinking status
Drinking	52 (10.2%)	124 (24.3%)
Nondrinking	306 (60.2%)	135 (26.5%)
Missing	150 (29.6%)	251 (49.2%)
Diabetes	190 (37.4%)
Non diabetes	318 (62.6%)
Hypertension	362 (71.3%)
Normal tension	146 (28.7%)

p^a value was calculated by Student ′s t-test. p^b value was calculated by Pearson ′s χ² test
p^c Mann–whitney test is used

ISSN: 1755-8794