Table 3 Association of CYP7B1 polymorphisms with CHD risk
From: The effect of CYP7B1 polymorphisms on the risk of coronary heart disease in Hainan Han population
SNP ID | Model | Allele/Genotype | Case N | Control N | OR (95% CI) | p |
|---|---|---|---|---|---|---|
rs7836768 | Allele | A | 595 | 616 | 1 | |
G | 419 | 404 | 1.07 (0.90–1.28) | 0.431 | ||
Codominant | AG | 239 | 71 | 0.90 (0.69–1.19) | 0.464 | |
GG | 90 | 262 | 1.27 (0.87–1.84) | 0.220 | ||
AA | 178 | 177 | 1 | |||
Dominant | AG-GG | 329 | 333 | 0.98 (0.76–1.27) | 0.878 | |
Recessive | AA-AG | 417 | 248 | 1 | ||
GG | 90 | 262 | 1.34 (0.96–1.89) | 0.090 | ||
Log-additive | – | – | – | 1.08 (0.90–1.29) | 0.427 | |
rs6472155 | Allele | A | 725 | 751 | 1 | |
G | 291 | 269 | 1.12 (0.92–1.36) | 0.252 | ||
Codominant | AG | 219 | 215 | 1.08 (0.83–1.39) | 0.575 | |
GG | 36 | 27 | 1.39 (0.82–2.35) | 0.226 | ||
AA | 253 | 268 | 1 | |||
Dominant | AG-GG | 255 | 242 | 1.11 (0.87–1.42) | 0.404 | |
Recessive | AA-AG | 472 | 483 | 1 | ||
GG | 36 | 27 | 1.34 (0.80–2.25) | 0.265 | ||
Log-additive | – | – | – | 1.12 (0.92–1.38) | 0.260 | |
rs2980003 | Allele | C | 653 | 666 | 1 | |
T | 363 | 352 | 1.05 (0.88–1.26) | 0.587 | ||
Codominant | TC | 233 | 230 | 1.05 (0.81–1.37) | 0.722 | |
TT | 65 | 61 | 1.09 (0.73–1.63) | 0.663 | ||
CC | 210 | 218 | 1 | |||
Dominant | TC-TT | 298 | 291 | 1.06 (0.82–1.36) | 0.657 | |
Recessive | CC-TC | 443 | 448 | 1 | ||
TT | 65 | 61 | 1.07 (0.73–1.55) | 0.738 | ||
Log-additive | – | – | – | 1.05 (0.87–1.26) | 0.626 |