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Table 4 Association between CYP7B1 polymorphisms and CHD risk stratified by age

From: The effect of CYP7B1 polymorphisms on the risk of coronary heart disease in Hainan Han population

SNP ID Model Genotype Case Control OR (95% CI) p Case Control OR (95% CI) p
 > 60 years  ≤ 60 years
rs7836768 Allele A 326 342 1   269 274 1  
   G 238 226 1.11 (0.87–1.40) 0.410 181 178 1.04 (0.79–1.35) 0.796
  Codominant AG 140 156 0.91 (0.89–1.32) 0.624 99 106 0.92 (0.61–1.39) 0.693
   GG 49 35 1.52 (0.89–2.58) 0.123 41 36 1.13 (0.66–1.93) 0.669
   AA 93 93 1   85 84 1  
  Dominant AG-GG 189 191 1.02 (0.71–1.45) 0.920 140 142 0.97 (0.66–1.43) 0.890
  Recessive AA-AG 233 249 1   184 190 1  
   GG 49 35 1.61 (1.00–2.59) 0.052 41 36 1.18 (0.72–1.93) 0.519
  Log-additive 1.15 (0.90–1.48) 0.266 1.03 (0.80–1.34) 0.806
rs6472155 Allele A 388 431 1   337 320 1  
   G 176 137 1.43 (1.10–1.86) 0.008 115 132 0.83 (0.62–1.11) 0.205
  Codominant AG 124 111 1.31 (0.92–1.86) 0.130 95 104 0.82 (0.56–1.19) 0.293
   GG 26 13 2.20 (1.07–4.49) 0.031 10 14 0.64 (0.27–1.50) 0.300
   AA 132 160 1   121 108 1  
  Dominant AG-GG 150 124 1.40 (1.00–1.95) 0.048 105 118 0.79 (0.55–1.15) 0.222
  Recessive AA-AG 256 271 1   216 212 1  
   GG 26 13 1.94 (0.97–3.90) 0.062 10 14 0.70 (0.30–1.61) 0.403
  Log-additive 1.39 (1.06–1.83) 0.018 0.81 (0.59–1.10) 0.180
rs2980003 Allele C 350 369 1   303 297 1  
   T 214 197 1.15 (0.90–1.46) 0.273 149 155 0.94 (0.72–1.24) 0.673
  Codominant TC 126 137 0.97 (0.68–1.39) 0.856 107 93 1.20 (0.81–1.77) 0.368
   TT 44 30 1.52 (0.89–2.61) 0.126 21 31 0.70 (0.38–1.31) 0.268
   CC 112 116 1   98 102 1  
  Dominant TC-TT 170 167 1.07 (0.76–1.50) 0.708 128 124 1.08 (0.74–1.56) 0.705
  Recessive CC-TC 238 253 1   205 195 1  
   TT 44 30 1.55 (0.94–2.57) 0.087 21 31 0.64 (0.36–1.16) 0.142
  Log-additive 1.15 (0.90–1.48) 0.261 0.94 (0.72–1.24) 0.574
  1. Bold indicate that P < 0.05 means the data are statistically significant
  2. OR, Odds ratio, 95% CI; 95% confidence intervals
  3. p values were calculated by logistic regression adjusted by age and gender
  4. p < 0.05 indicates statistical significance