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Table 5 Association between CYP7B1 polymorphisms and CHD risk stratified by gender

From: The effect of CYP7B1 polymorphisms on the risk of coronary heart disease in Hainan Han population

SNP ID Model Genotype Case Control OR (95% CI) p Case Control OR (95% CI) p
Women Men
rs7836768 Allele A 205 223 1   390 393 1  
   G 141 125 1.23 (0.90–1.67) 0.191 278 279 1.00 (0.81–1.25) 0.971
  Codominant AG 89 95 1.00 (0.63–1.59) 0.989 150 167 / /
   GG 26 15 1.87 (0.90–3.89) 0.096 64 56 1.08 (0.69–1.68) 0.734
   AA 58 64 1   120 113 1  
  Dominant AG-GG 115 110 1.12 (0.72–1.75) 0.616 214 223 0.90 (0.66–1.24) 0.537
  Recessive AA-AG 147 159 1   270 280 1  
   GG 26 15 1.86 (0.94–3.67) 0.073 64 56 1.19 (0.80–1.77) 0.392
  Log-additive 1.24 (0.89–1.73) 0.201 1.01 (0.81–1.25) 0.961
rs6472155 Allele A 239 266 1   486 485 1  
   G 109 82 1.48 (1.06–2.07) 0.022 182 187 0.97 (0.76–1.23) 0.812
  Codominant AG 73 70 1.21 (0.78–1.89) 0.393 146 145 / /
   GG 18 6 3.17 (1.19–8.44) 0.021 18 21 1.37 (0.83–2.26) 0.652
   AA 83 98 1   170 170 1  
  Dominant AG-GG 91 76 1.37 (0.89–2.10) 0.148 164 166 0.99 (0.73–1.34) 0.937
  Recessive AA-AG 156 168 1   316 315 1  
   GG 18 6 2.91 (1.12–7.58) 0.029 18 21 0.86 (0.45–1.64) 0.637
  Log-additive 1.45 (1.02–2.06) 0.037 0.97 (0.75–1.25) 0.803
rs2980003 Allele C 225 215 1   428 451 1  
   T 123 133 0.88 (0.65–1.20) 0.432 240 219 1.16 (0.92–1.45) 0.212
  Codominant TC 81 81 0.92 (0.58–1.46) 0.732 152 149 / /
   TT 21 26 0.73 (0.37–1.43) 0.362 44 35 1.37 (0.83–2.26) 0.220
   CC 72 67 1   138 151 1  
  Dominant TC-TT 102 107 0.88 (0.57–1.35) 0.551 196 184 1.16 (0.86–1.58) 0.334
  Recessive CC-TC 153 148 1   290 300 1  
   TT 21 26 0.76 (0.41–1.43) 0.398 44 35 1.29 (0.81–2.08) 0.286
  Log-additive 0.87 (0.64–1.19) 0.394 1.15 (0.92–1.45) 0.220
  1. Bold indicate that P < 0.05 means the data are statistically significant
  2. OR, Odds ratio, 95% CI; 95% confidence intervals
  3. p values were calculated by logistic regression adjusted by age and gender
  4. p < 0.05 indicates statistical significance