Fig. 1

Images of a CT scan and b bone scintigraphy at the initial diagnosis of Gleason grade group 5 PC (PSA: 13.37 ng/mL), and those of c CT scan and d bone scintigraphy at the diagnosis of ASCP (PSA: 0.02 ng/mL), respectively. During the course, the prostatic mass grew remarkably (a → c) and the number of bone metastases increased (b → d), despite maintaining a low PSA level. Abbreviations: ASCP, adenosquamous carcinoma of the prostate; CT, computed tomography; PC, prostate cancer; PSA, prostate-specific antigen