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Table 2 Basic characteristics and allele frequencies of the candidate SNPs in MAD1L1 and TSNARE1

From: MAD1L1 and TSNARE gene polymorphisms are associated with schizophrenia susceptibility in the Han Chinese population

SNP

Chr

Position

Gene

Role

Allele minor/major

MAF

HWE

HaploReg

Case

Control

Case

Control

rs10275045

7

1881190

MAD1L1

Intron

T/C

0.435

0.447

0.988

0.315

Motifs changed; NHGRI/EBI GWAS hits; GRASP QTL Hits; Selected eQTL hits

rs12666575

7

1964786

MAD1L1

Intron

T/C

0.458

0.456

0.116

0.170

Enhancer histone marks; DNAse; NHGRI/EBI GWAS hits; Selected eQTL hits

rs1107592

7

2001797

MAD1L1

Intron

A/G

0.453

0.465

0.029

0.278

Enhancer histone marks; DNAse; Motifs changed; NHGRI/EBI GWAS hits; GRASP QTL Hits; Selected eQTL hits

rs4976976

8

142230292

TSNARE1

Intron

A/G

0.505

0.499

0.016

0.207

DNAse; Motifs changed

rs67756423

8

142252164

TSNARE1

Intron

C/A

0.360

0.372

0.019

0.147

Selected eQTL hits

  1. SNP: Single nucleotide polymorphism; Chr: chromosome; MAF: Minor allele frequency; HWE: Hardy–Weinberg equilibrium; OR: Odds ratio; 95% CI: 95% confidence interval
  2. p values were calculated from χ2 test