Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients

Table 2 Patient characteristics for POCD analysis (n = 452)

Characteristic	POCD (n = 46) (10.2%)	No POCD (n = 406) (89.8%)	P
Characteristic	n = 452
Age [years]	74 [70; 77]	71 [68; 75]	0.006^a
Sex
Female	26 (56.5%)	158 (38.9%)	0.02^b
Charlson Comorbidity Index	1.74 ± 1.6	1.18 ± 1.4	0.006^a
Duration of anesthesia (min)	202 [120; 308]	198 [121; 292]	0.99^a

Data is shown as median [IQR 25; IQR 75], or as mean ± SD. Categorical data is shown as frequencies (percentages). Differences between patient groups with and without POD were evaluated with Mann–Whitney U test (a) or Chi-Square Test (b), whereas a P ≤ 0.05 was considered as statistically significant
IQR, interquartile range; SD, standard deviation

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