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Table 1 Demographic data of the study subjects

From: Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects

Clinical features Phase I Phase II Combined
sALS (n = 371) Control (n = 711) sALS (n = 300) Control (n = 1076) sALS (n = 671) Control_2 (n = 1787)
Sex, M/F (ratio) 227/144 (1.58:1) 283/428 (0.66:1) 183/117 (1.56:1) 453/623 (0.73:1) 410/261 (1.57:1) 736/1051 (0.70:1)
Age (year, mean ± SD) 55.13 ± 10.28 69.41 ± 8.42 55.16 ± 9.82 69.83 ± 7.70 55.14 ± 9.97 69.66 ± 7.91
Age at onset (year, mean ± SD) 53.42 ± 10.28 53.49 ± 9.56 53.45 ± 9.96
Site of onset, bulbar (%) 73/371 (19.68%) 59/300 (19.61) 132/671 (19.67%)
  1. sALS, sporadic amyotrophic lateral sclerosis; AAO, age at onset