Skip to main content

Table 4 Stratified analyses of rs2585405 polymorphism and NIHL risk

From: A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population

Group Genotype noise exposed (years) Expose level with noise (dB)
 ≤ 16  > 16  ≤ 85 85–92  > 92
Case GG 27 71 63 26 9
  GC 33 165 124 59 15
  CC 24 112 78 41 17
Control GG 34 106 76 55 9
  GC 80 345 248 139 38
  CC 55 217 150 94 28
Pa   0.11 0.17 0.03 0.93 0.23
Adjusted OR   1.33 1.11 1.23 1.02 1.07
(95%CI)b   (0.93–1.90) (0.92–1.34) (0.99–1.53) (0.76–1.37) (0.61–1.87)
Case GG 27 71 63 26 9
  GC/CC 57 277 202 100 32
Control GG 34 106 76 55 9
  GC/CC 135 562 398 233 66
Pa   0.04 0.07 0.01 0.72 0.16
Adjusted OR   1.88 1.37 1.64 1.10 1.92
(95%CI)b   (1.03–3.42) (0.98–1.91) (1.12–2.38) (0.65–1.85) (0.67–5.52)
  1. aTwo-sided χ2 test
  2. bAdjusted for age, sex, alcohol and tobacco use in a logistic regression model