Skip to main content

Table 1 Main characteristics of all case–control studies included in meta-analysis

From: Ethnicity-stratified analysis of the association between XRCC3 Thr241Met polymorphism and leukemia: an updated meta-analysis

Literature Ethnics (country) Genotyping methods Source of control Sample size HWE conformity NOS Genotype frequency (Case) Genotype frequency (Control) Mean age (Case) Mean age (Control) Year
CC CT TT CC CT TT
Seedhouse et al. [15] Caucasian (United Kingdom) PCR–RFLP PB 123/175 Yes 8 99 87 30 92 64 19 63 (17–96) 52 (15–97) 2002
Seedhouse et al. [16] Caucasian (United Kingdom) PCR–RFLP PB 216/175 Yes 8 119 103 38 92 64 19 64 (11–96) 50 (15–97) 2004
Matullo et al. [17] Caucasian (European countries) TaqMan PB 169/1094 Yes 8 61 90 18 383 544 167 35–74 35–74 2006
Bhatla et al. [18] Caucasian (United States) TaqMan PB 282/646 Yes 9 125 157 47 253 309 84 NR NR 2008
Zhang et al. [19] Asian (China) PCR–RFLP PB 148/458 Yes 7 133 13 2 403 46 9 42 (23–76) 42 (23–76) 2009
Hamdy et al. [20] African (Egypt) Direct sequencing PB 50/30 Yes 6 22 20 8 18 9 3 14–65 12–46 2011
Liu et al. [21] Asian (China) PCR–RFLP PB 379/806 Yes 7 55 39 11 627 73 4 32 (5–69) 42 (15–90) 2011
Nina et al. [23] Caucasian (Slovenia) TaqMan PB 20/39 Yes 7 6 8 6 15 19 5 9.5 (2–34) 10 (0–37) 2012
Abramenko et al. [22] Caucasian (Ukraine) PCR–RFLP PB 159/73 Yes 8 74 60 25 30 33 10 57.78 ± 1.09 58.16 ± 0.91 2012
Sorour et al. [25] African (Egypt) PCR–RFLP PB 90/60 Yes 7 24 63 3 12 42 6 16–60 18–69 2013
Banescu et al. [24] Caucasian (Romania) PCR–RFLP PB 78/121 Yes 7 36 30 12 85 27 9 51.76 ± 17.1 58.84 ± 12.9 2013
Smolkova et al. [27] Caucasian (Germany) TaqMan PB 459/549 Yes 9 178 216 65 216 256 77 6.9 ± .4.4 32 ± 8.1 2014
Banescu et al. [26] Caucasian (Romania) PCR–RFLP PB 78/121 Yes 7 64 70 22 85 79 16 51.5 ± 1.1 49.8 ± 2.1 2014
Miao et al. [28] Asian (China) TaqMan PB 545/1034 Yes 9 470 45 3 902 130 1 46 (8–80) 43 (8–85) 2015
Mutlu et al. [29] Caucasian (Turkey) PCR–RFLP HB 25/30 Yes 7 9 12 4 13 11 6 NR NR 2015
Pei et al. [30] Asian (Taiwan) PCR–RFLP PB 266/266 Yes 7 214 39 13 241 19 6 7.0 ± 4.4 8.3 ± 4.8 2018
  1. PB population-based, HWE Hardy–Weinberg equilibrium, RFLP restricted fragment length polymorphism, NOS Newcastle–Ottawa Score, NR not reported