Fig. 1From: Whole genome sequencing in the diagnosis of primary ciliary dyskinesiaGenomics England Ltd (Genomics England Ltd) variant filtering and tiering strategy for single nucleotide variants (SNVs) or small insertions or deletions. Tier 1 and tier 2 variants were returned to recruiting Genome Medicine Centres (GMC) for variant review and classification following American College of Medical Genetics guidelines. Tier 3 variants were available for review in the research environment. Primary ciliary disorders PanelApp gene panel can be found in Table 1, non-CF bronchiectasis PanelApp gene panel can be found in Table 2Back to article page