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Table 1 Characteristics of patients with acute myeloid leukemia (AML)

From: Identification of seven novel ferroptosis-related long non-coding RNA signatures as a diagnostic biomarker for acute myeloid leukemia

Characteristics Patients (N,%) (N,%) P
Training group (n = 92) Validation group (n = 38)
Sex     0.948
Female 61 (46.9) 43 (46.7) 18 (47.4)  
Male 69 (53.1) 49 (53.3) 20 (52.6)  
Age,years     0.123
 ≤ 55 65 (50.0) 50 (54.3) 15 (39.5)  
 > 55 65 (50.0) 42 (45.7) 23 (60.5)  
FAB subtype     0.706
 M0 12 (9.2) 11 (12.0) 1 (2.6)  
 M1 31 (23.8) 20 (21.7) 11 (28.9)  
 M2 32 (24.6) 21 (22.8) 11 (28.9)  
 M3 13 (10.0) 10 (10.8) 3 (7.9)  
 M4 27 (20.8) 19 (20.7) 8 (21.1)  
 M5 12 (9.2) 8 (8.7) 4 (10.6)  
 M6 2 (1.6) 2 (2.2) 0 (0)  
 M7 1 (0.8) 1 (1.1) 0 (0)  
Cytogenetics risk category     
 Favorable 29 (22.3) 24 (26.1) 5 (13.2) 0.349
 Intermediate/Normal 72 (55.4) 50 (54.3) 22 (57.9)  
 Poor 27 (20.8) 17 (18.5) 10 (26.3)  
 Unknow 2 (1.5) 1 (1.1) 1 (2.6)  
FLT3 mutation     0.937
 Positive 33 (25.4) 24 (26.1) 9 (23.7)  
 Negative 93 (71.5) 65 (70.6) 28 (73.7)  
 Unknow 4 (3.1) 3 (3.3) 1 (2.6)  
IDH1 R132     0.704
 Positive 13 (10.0) 10 (10.9) 3 (7.9)  
 Negative 116 (89.2) 81 (88.0) 35 (92.1)  
 Unknow 1 (0.8) 1 (1.1) 0 (0)  
IDH1 R140     0.337
 Positive 11 (8.5) 6 (6.5) 5 (13.5)  
 Negative 116 (89.9) 85 (92.4) 31 (83.8)  
 Unknow 2 (1.6) 1 (1.1) 1 (2.7)  
NPMc     0.811
 Positive 31 (23.8) 22 (23.9) 9 (23.7)  
 Negative 98 (75.4) 69 (75.0) 29 (76.3)  
 Unknow 1 (0.8) 1 (1.1) 0 (0)  
Follow-up state     0.123
 Alive 51 (39.2) 40 (43.5) 11 (28.9)  
 Died 79 (60.8) 52 (56.5) 27 (71.1)  
  1. FAB French–American–British, FLT3 FMS-like tyrosine kinase 3, IDH1 isocitrate dehydrogenase 1, NPMc nucleophosmin mutations