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Table 2 Information of the 5 miRNAs most relevant to the common hub genes

From: Identification and validation of pivotal genes related to age-related meniscus degeneration based on gene expression profiling analysis and in vivo and in vitro models detection

  Target genes Position Energy Binding region length P-value
hsa-miR-6810-5p RRM2,CDK1,TIMP1 3UTR  − 24.1 29 0.01664477
hsa-miR-4676-5p RRM2,CDK1,TIMP1 3UTR  − 22.9 18 0.007139029
hsa-miR-6877-5p RRM2,CDK1,TIMP1 3UTR  − 21.8 24 0.000873123
hsa-miR-8085 RRM2,CDK1,TIMP1 3UTR  − 22.6 25 0.006883728
hsa-miR-6133 RRM2,AURKB,TIMP1 3UTR  − 22.4 17 0.001472693
  1. RRM2 ribonucleotide reductase regulatory subunit M2; AURKB aurora kinase B; CDK1 cyclin dependent kinase 1; TIMP1 tissue inhibitor of metalloproteinases 1