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Table 4 Associations of hsa_circ_000780 levels with clinicopathological characteristics in GC

From: The circular RNA hsa_circ_000780 as a potential molecular diagnostic target for gastric cancer

Characteristics

No. of patients (n = 78, %)

Expression levels of has_circ_000780 (Mean ± SD, × 10–4)

P value

Age (year)

 ≥ 60

45 (57.7)

5.97 ± 1.65

1.000

 < 60

33 (42.3)

5.97 ± 2.12

 

Sex

 Male

40 (51.3)

6.32 ± 3.09

0.112

 Female

38 (48.7)

7.45 ± 3.09

 

Tumor location

 Sinuses ventriculi

39 (50.0)

6.20 ± 3.29

0.418

 Cardia

17 (21.8)

7.80 ± 3.04

 

 Corpora ventriculi

13 (16.7)

6.90 ± 2.57

 

 Others

9 (11.5)

7.98 ± 2.96

 

Diameter (cm)

 ≥ 5

38 (48.7)

6.03 ± 3.16

0.020

 < 5

40 (51.3)

7.67 ± 2.91

 

Differentiation

 Well

9 (11.5)

7.29 ± 2.55

0.303

 Moderate

36 (46.2)

7.38 ± 3.04

 

 Poor

32 (41.3)

6.20 ± 3.20

 

Stage

 Early

21 (26.9)

5.08 ± 2.13

0.001

 Advanced

57 (73.1)

7.53 ± 3.19

 

Pathologic diagnosis

 Signet ring cell cancer

11 (14.1)

5.21 ± 2.80

0.055

 Adenocarcinoma

67 (85.9)

7.14 ± 3.11

 

T stage

 T1 and T2

25 (32.1)

5.78 ± 2.84

0.029

 T3 and T4

53 (67.9)

7.38 ± 3.14

 

Lymphatic metastasis

 N0

28 (56.0)

6.63 ± 3.44

0.625

 N1-2

50 (44.0)

7.01 ± 2.96

 

Distal metastasis

 M0

68 (87.2)

5.81 ± 3.74

0.345

 M1

10 (12.8)

7.03 ± 3.02

 

Venous invasion

 Absent

41 (51.3)

6.19 ± 3.20

0.042

 Present

37 (51.3)

7.62 ± 2.89

 

Carcinoembryonic antigen

 Positive

25 (52.6)

5.22 ± 2.63

0.001

 Negative

53 (47.1)

7.65 ± 3.05

 

CA19-9 (Tissue)

 Positive

21 (26.9)

4.67 ± 2.14

0.001

 Negative

57 (73.1)

7.68 ± 3.05

 
  1. Bold values: P < 0.05