From: The circular RNA hsa_circ_000780 as a potential molecular diagnostic target for gastric cancer
Characteristics | No. of patients (n = 78, %) | Expression levels of has_circ_000780 (Mean ± SD, × 10–4) | P value |
---|---|---|---|
Age (year) | |||
 ≥ 60 | 45 (57.7) | 5.97 ± 1.65 | 1.000 |
 < 60 | 33 (42.3) | 5.97 ± 2.12 |  |
Sex | |||
 Male | 40 (51.3) | 6.32 ± 3.09 | 0.112 |
 Female | 38 (48.7) | 7.45 ± 3.09 |  |
Tumor location | |||
 Sinuses ventriculi | 39 (50.0) | 6.20 ± 3.29 | 0.418 |
 Cardia | 17 (21.8) | 7.80 ± 3.04 |  |
 Corpora ventriculi | 13 (16.7) | 6.90 ± 2.57 |  |
 Others | 9 (11.5) | 7.98 ± 2.96 |  |
Diameter (cm) | |||
 ≥ 5 | 38 (48.7) | 6.03 ± 3.16 | 0.020 |
 < 5 | 40 (51.3) | 7.67 ± 2.91 |  |
Differentiation | |||
 Well | 9 (11.5) | 7.29 ± 2.55 | 0.303 |
 Moderate | 36 (46.2) | 7.38 ± 3.04 |  |
 Poor | 32 (41.3) | 6.20 ± 3.20 |  |
Stage | |||
 Early | 21 (26.9) | 5.08 ± 2.13 | 0.001 |
 Advanced | 57 (73.1) | 7.53 ± 3.19 |  |
Pathologic diagnosis | |||
 Signet ring cell cancer | 11 (14.1) | 5.21 ± 2.80 | 0.055 |
 Adenocarcinoma | 67 (85.9) | 7.14 ± 3.11 |  |
T stage | |||
 T1 and T2 | 25 (32.1) | 5.78 ± 2.84 | 0.029 |
 T3 and T4 | 53 (67.9) | 7.38 ± 3.14 |  |
Lymphatic metastasis | |||
 N0 | 28 (56.0) | 6.63 ± 3.44 | 0.625 |
 N1-2 | 50 (44.0) | 7.01 ± 2.96 |  |
Distal metastasis | |||
 M0 | 68 (87.2) | 5.81 ± 3.74 | 0.345 |
 M1 | 10 (12.8) | 7.03 ± 3.02 |  |
Venous invasion | |||
 Absent | 41 (51.3) | 6.19 ± 3.20 | 0.042 |
 Present | 37 (51.3) | 7.62 ± 2.89 |  |
Carcinoembryonic antigen | |||
 Positive | 25 (52.6) | 5.22 ± 2.63 | 0.001 |
 Negative | 53 (47.1) | 7.65 ± 3.05 |  |
CA19-9 (Tissue) | |||
 Positive | 21 (26.9) | 4.67 ± 2.14 | 0.001 |
 Negative | 57 (73.1) | 7.68 ± 3.05 |  |