Table 5 The association analysis stratified for tumor location

Colon

Codominant

C/C

305 (61%)

105 (51%)

Ref

2.17e−05

Ref

5.30e−05

C/T

161 (32.2%)

62 (30.1%)

1.12 (0.77–1.62)

1.1 (0.76–1.6)

T/T

34 (6.8%)

39 (18.9%)

3.33 (2–5.55)

3.27 (1.93–5.54)

Dominant

C/C

305 (61%)

105 (51%)

Ref

0.014404

Ref

0.021843

C/T–T/T

195 (39%)

101 (49%)

1.5 (1.08–2.09)

1.48 (1.06–2.07)

Recessive

C/C–C/T

466 (93.2%)

167 (81.1%)

Ref

4.31e−06

Ref

1.04e−05

T/T

34 (6.8%)

39 (18.9%)

3.2 (1.96–5.24)

3.16 (1.9–5.26)

Over dominant

C/C–T/T

339 (67.8%)

144 (69.9%)

Ref

0.583813

Ref

0.558616

C/T

161 (32.2%)

62 (30.1%)

0.91 (0.64–1.29)

0.9 (0.63–1.29)

log-Additive

0, 1, 2

500 (70.8%)

206 (29.2%)

1.6 (1.26–2.02)

9.44e−05

1.57 (1.24–2)

0.000217

Rectosigmoid

Codominant

C/C

305 (61%)

110 (51.6%)

Ref

7.24e−10

Ref

5.88e−09

C/T

161 (32.2%)

50 (23.5%)

0.86 (0.59–1.27)

0.79 (0.53–1.18)

T/T

34 (6.8%)

53 (24.9%)

4.32 (2.67–7)

4.16 (2.48–6.96)

Dominant

C/C

305 (61%)

110 (51.6%)

Ref

0.020807

Ref

0.080438

C/T–T/T

195 (39%)

103 (48.4%)

1.46 (1.06–2.02)

1.35 (0.96–1.9)

Recessive

C/C–C/T

466 (93.2%)

160 (75.1%)

Ref

1.17e−10

Ref

1.49e−09

T/T

34 (6.8%)

53 (24.9%)

4.54 (2.85–7.24)

4.5 (2.73–7.41)

Over dominant

C/C–T/T

339 (67.8%)

163 (76.5%)

Ref

0.017874

Ref

0.006936

C/T

161 (32.2%)

50 (23.5%)

0.65 (0.45–0.93)

0.59 (0.4–0.87)

log-Additive

0, 1, 2

500 (70.1%)

213 (29.9%)

1.71 (1.37–2.14)

2.54e−06

1.64 (1.29–2.07)

3.75e−05