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Table 6 The associations of the clinical characteristics within genotype

From: Association of MTHFR C677T variant genotype with serum folate and Vit B12 in Iranian patients with colorectal cancer or adenomatous polyps

Genotype Clinical feature Characteristic Control Case OR (95% CI) P-value
C/C Sex Female 155 95 Ref  
Male 150 120 1.31 (0.92–1.85) 0.136287
C/T Female 89 54 Ref  
Male 72 58 1.33 (0.82–2.15) 0.25070
T/T Female 17 51 Ref  
Male 17 41 0.8 (0.37–1.77) 0.587
C/C Age  < 45 142 50 Ref  
 ≥ 45 163 165 2.87 (1.95–4.24) 9.77e−08
C/T  < 45 71 23 Ref  
 ≥ 45 90 89 3.05 (1.75–5.31) 7.88e−05
T/T  < 45 16 13 Ref  
 ≥ 45 18 79 5.4 (2.21–13.19) 0.000214
C/C Addiction No 234 180 Ref  
Yes 71 35 0.64 (0.41–1) 0.05210
C/T No 131 95 Ref  
Yes 30 17 0.78 (0.41–1.5) 0.4577
T/T No 22 78 Ref  
Yes 12 14 0.33 (0.13–0.81) 0.016
  1. Bold indicates a p-value less than 0.05 is statistically significant