Table 1 Clinical characteristics of the population analyzed n = 135
Clinical features | |
Age | |
Mean ± SD (range) | 47 (15–92) |
Median | 48 |
Sex | |
F | 65 (48.1) |
M | 70 (51.9) |
Laboratory data | |
PB Blast count | |
Mean ± SD (range) | 58 ± 28 (0–99) |
Median | 60 |
Mean WBC count, 109/L (range) | 154 (0.2–456) |
Mean hemoglobin level, g/L (range) | 10.61 (2.60–91) |
Mean platelet count, 109/L (range) | 46 (3–241) |
Mean DHL (range) | 635 (89–3921) |
Biologic characteristics | |
Immunophenotype (%) | |
M1 | 4 (3.0) |
M2 | 42 (31.1) |
M4 | 81 (60.0) |
M5 | 2 (1.5) |
M6 | 4 (3.0) |
M7 | 2 (1.5) |
Cytogenetics | |
Unsuccessful karyotype | 63(46.7) |
Normal karyotype | 68(50.4) |
Abnormal karyotype | 4 (3.0) |
Treatment scheme | |
3 + 7 | 108 (80) |
Mini 3 + 7 | 16 (11.9) |
2 + 5 | 3 (2.2) |
ARA C SC | 8 (5.9) |
Response | |
Response complete | 55 (40.7) |
Remission partial | 16 (11.9) |
Refractory disease | 28 (20.7) |
Death in aplasia | 30 (22.2) |
Death by undetermined cause | 6 (4.40) |